Of tuberculosis and non-tuberculous mycobacterial infections–a comparative analysis of epidemiology, diagnosis and treatment

R Gopalaswamy, S Shanmugam, R Mondal… - Journal of biomedical …, 2020 - Springer
Pulmonary diseases due to mycobacteria cause significant morbidity and mortality to human
health. In addition to tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), recent …

Immunological impacts of diabetes on the susceptibility of Mycobacterium tuberculosis

B Ayelign, M Negash, M Genetu… - Journal of …, 2019 - Wiley Online Library
The interaction between diabetes and major world infections like TB is a major public health
concern because of rapidly rising levels of diabetes. The dual burden of tuberculosis (TB) …

Association of blood glucose control and outcomes in patients with COVID-19 and pre-existing type 2 diabetes

L Zhu, ZG She, X Cheng, JJ Qin, XJ Zhang, J Cai, F Lei… - Cell metabolism, 2020 - cell.com
Summary Type 2 diabetes (T2D) is a major comorbidity of COVID-19. However, the impact of
blood glucose (BG) control on the degree of required medical interventions and on mortality …

[HTML][HTML] Anti-diabetics and antimicrobials: Harmony of mutual interplay

WAH Hegazy, AAH Rajab, ASA Lila… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Diabetes is one of the four major non-communicable diseases, and appointed by the world
health organization as the seventh leading cause of death worldwide. The scientists have …

Modulating the foreign body response of implants for diabetes treatment

BN Kharbikar, GS Chendke, TA Desai - Advanced drug delivery reviews, 2021 - Elsevier
Diabetes Mellitus is a group of diseases characterized by high blood glucose levels due to
patients' inability to produce sufficient insulin. Current interventions often require implants …

[HTML][HTML] Comorbid illnesses are associated with altered adaptive immune responses to SARS-CoV-2

KQ Krystle, S Fischinger, MT Smith, C Atyeo… - JCI insight, 2021 - ncbi.nlm.nih.gov
Comorbid medical illnesses, such as obesity and diabetes, are associated with more severe
COVID-19, hospitalization, and death. However, the role of the immune system in mediating …

Bioinformatics analysis and consistency verification of a novel tuberculosis vaccine candidate HP13138PB

P Cheng, F Jiang, G Wang, J Wang, Y Xue… - Frontiers in …, 2023 - frontiersin.org
Background With the increasing incidence of tuberculosis (TB) and the shortcomings of
existing TB vaccines to prevent TB in adults, new TB vaccines need to be developed to …

In silico Analysis of Peptide-Based Biomarkers for the Diagnosis and Prevention of Latent Tuberculosis Infection

P Cheng, L Wang, W Gong - Frontiers in microbiology, 2022 - frontiersin.org
Background Latent tuberculosis infection (LTBI) is the primary source of active tuberculosis
(ATB), but there are no specific methods for diagnosing and preventing LTBI. Methods …

The cause–effect relation of tuberculosis on incidence of diabetes mellitus

MK Bisht, P Dahiya, S Ghosh… - Frontiers in cellular and …, 2023 - frontiersin.org
Tuberculosis (TB) is one of the oldest human diseases and is one of the major causes of
mortality and morbidity across the Globe. Mycobacterium tuberculosis (Mtb), the causal …

PP19128R, a Multiepitope Vaccine Designed to Prevent Latent Tuberculosis Infection, Induced Immune Responses In Silico and In Vitro Assays

F Jiang, C Peng, P Cheng, J Wang, J Lian, W Gong - Vaccines, 2023 - mdpi.com
Background: Latent tuberculosis infection (LTBI) is the primary source of active tuberculosis
(ATB), but a preventive vaccine against LTBI is lacking. Methods: In this study, dominant …