Mesenchymal stem cell therapy for the treatment of inflammatory diseases: challenges, opportunities, and future perspectives
Mesenchymal stem cells (MSCs) are promising alternative agents for the treatment of
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …
Life is 3D: boosting spheroid function for tissue engineering
MW Laschke, MD Menger - Trends in biotechnology, 2017 - cell.com
Spheroids provide a 3D environment with intensive cell–cell contacts. As a result of their
excellent regenerative properties and rapid progress in their high-throughput production …
excellent regenerative properties and rapid progress in their high-throughput production …
Engineering multi‐cellular spheroids for tissue engineering and regenerative medicine
Multi‐cellular spheroids are formed as a 3D structure with dense cell–cell/cell–extracellular
matrix interactions, and thus, have been widely utilized as implantable therapeutics and …
matrix interactions, and thus, have been widely utilized as implantable therapeutics and …
Combination of 3D printing and electrospinning techniques for biofabrication
DL Yang, F Faraz, JX Wang… - Advanced Materials …, 2022 - Wiley Online Library
This review presents the different combination methods of 3D printing and electrospinning
processes and discusses the advantages of each method. Also, the applications of products …
processes and discusses the advantages of each method. Also, the applications of products …
[HTML][HTML] Fat therapeutics: the clinical capacity of adipose-derived stem cells and exosomes for human disease and tissue regeneration
L Shukla, Y Yuan, R Shayan, DW Greening… - Frontiers in …, 2020 - frontiersin.org
Fat grafting is a well-established surgical technique used in plastic surgery to restore
deficient tissue, and more recently, for its putative regenerative properties. Despite more …
deficient tissue, and more recently, for its putative regenerative properties. Despite more …
Three-dimensional spheroid culture of human mesenchymal stem cells: offering therapeutic advantages and in vitro glimpses of the in vivo state
BL Yen, CC Hsieh, PJ Hsu, CC Chang… - Stem cells …, 2023 - academic.oup.com
As invaluable as the standard 2-dimensional (2D) monolayer in vitro cell culture system has
been, there is increasing evidence that 3-dimensional (3D) non-adherent conditions are …
been, there is increasing evidence that 3-dimensional (3D) non-adherent conditions are …
[HTML][HTML] The therapeutic potential of three-dimensional multipotent mesenchymal stromal cell spheroids
Y Petrenko, E Syková, Š Kubinová - Stem cell research & therapy, 2017 - Springer
The efficiency of clinical trials involving transplantation of multipotent mesenchymal stromal
cells (MSCs) is often insufficient due to harsh conditions present within the target tissue …
cells (MSCs) is often insufficient due to harsh conditions present within the target tissue …
Three-dimensional aggregates of mesenchymal stem cells: cellular mechanisms, biological properties, and applications
Mesenchymal stem cells (MSCs) are primary candidates in cell therapy and tissue
engineering and are being tested in clinical trials for a wide range of diseases. Originally …
engineering and are being tested in clinical trials for a wide range of diseases. Originally …
[HTML][HTML] Scalable production of human mesenchymal stromal cell-derived extracellular vesicles under serum-/xeno-free conditions in a microcarrier-based bioreactor …
M de Almeida Fuzeta, N Bernardes… - Frontiers in Cell and …, 2020 - frontiersin.org
Mesenchymal stromal cells (MSC) hold great promise for tissue engineering and cell-based
therapies due to their multilineage differentiation potential and intrinsic immunomodulatory …
therapies due to their multilineage differentiation potential and intrinsic immunomodulatory …
[HTML][HTML] Increased mesenchymal stem cell functionalization in three-dimensional manufacturing settings for enhanced therapeutic applications
D Kouroupis, D Correa - Frontiers in bioengineering and …, 2021 - frontiersin.org
Mesenchymal stem/stromal cell (MSC) exist within their in vivo niches as part of
heterogeneous cell populations, exhibiting variable stemness potential and supportive …
heterogeneous cell populations, exhibiting variable stemness potential and supportive …