Gasotransmitters in cancer: from pathophysiology to experimental therapy

C Szabo - Nature reviews Drug discovery, 2016 - nature.com
The three endogenous gaseous transmitters—nitric oxide (NO), carbon monoxide (CO) and
hydrogen sulfide (H2S)—regulate a number of key biological functions. Emerging data have …

The mechanism of cone cell death in Retinitis Pigmentosa

PA Campochiaro, TA Mir - Progress in retinal and eye research, 2018 - Elsevier
Retinitis Pigmentosa (RP) is a group of diseases in which one of a large number of
mutations causes death of rod photoreceptors. After rods die, cone photoreceptors slowly …

Use of electronic cigarettes (e-cigarettes) impairs indoor air quality and increases FeNO levels of e-cigarette consumers

W Schober, K Szendrei, W Matzen… - International journal of …, 2014 - Elsevier
Despite the recent popularity of e-cigarettes, to date only limited data is available on their
safety for both users and secondhand smokers. The present study reports a comprehensive …

Endothelial dysfunction and vascular disease

PM Vanhoutte, H Shimokawa, EHC Tang… - Acta …, 2009 - Wiley Online Library
The endothelium can evoke relaxations (dilatations) of the underlying vascular smooth
muscle, by releasing vasodilator substances. The best characterized endothelium‐derived …

Regulation of the cerebral circulation: role of endothelium and potassium channels

FM Faraci, DD Heistad - Physiological reviews, 1998 - journals.physiology.org
Faraci, Frank M., and Donald D. Heistad. Regulation of the Cerebral Circulation: Role of
Endothelium and Potassium Channels. Physiol. Rev. 78: 53–97, 1998.—Several new …

Electrochemical monitoring of single cell secretion: vesicular exocytosis and oxidative stress

C Amatore, S Arbault, M Guille, F Lemaitre - Chemical reviews, 2008 - ACS Publications
Communication between cellular organisms occurs, among other mechanisms, through the
release of specific biochemical or chemical messengers by an emitting cell, generally …

Microglia as effector cells in brain damage and repair: focus on prostanoids and nitric oxide

L Minghetti, G Levi - Progress in neurobiology, 1998 - Elsevier
Microglial cells are believed to play an active role in brain inflammatory, immune and
degenerative processes. Depending on the magnitude of microglial reaction, on the type of …

Cytokines and their roles in pancreatic islet β-cell destruction and insulin-dependent diabetes mellitus

A Rabinovitch, WL Suarez-Pinzon - Biochemical pharmacology, 1998 - Elsevier
Insulin-dependent diabetes mellitus (IDDM) is a disease that results from autoimmune
destruction of the insulin-producing β-cells in the pancreatic islets of Langerhans. The …

Pathogenesis and pathophysiology of pneumococcal meningitis

U Koedel, WM Scheld, HW Pfister - The Lancet infectious diseases, 2002 - thelancet.com
Until the introduction of antibiotics in the 1930s and 1940s, acute bacterial meningitis was
fatal in most cases. Since then it has become curable with a variable mortality and morbidity …

Evidence for the formation of a novel nitrosothiol from the gaseous mediators nitric oxide and hydrogen sulphide

M Whiteman, L Li, I Kostetski, SH Chu, JL Siau… - Biochemical and …, 2006 - Elsevier
The gaseous mediators hydrogen sulphide (H2S) and nitric oxide (NO) are synthesised in
the body from l-cysteine and l-arginine, respectively. In the cardiovascular system, NO is an …