The liver is the commonest site of metastatic disease for patients with colorectal cancer, with
at least 25% developing colorectal liver metastases (CRLM) during the course of their …

Liver metastasis is the commonest form of distant metastasis in colorectal cancer. Selection
criteria for surgery and liver-directed therapies have recently been extended. However …

Up to a fifth of patients with colorectal cancer (CRC) present with synchronous hepatic
metastases. In patients with CRC who present without intestinal obstruction or perforation …

Background: Chemotherapy is increasingly used in colorectal liver metastases (CRLMs)
even when they are initially resectable. The aim of our study was to address the still pending …

Objective This study was designed to evaluate the long-time outcome of patients with
colorectal liver metastasis (CRLM) undergoing different types of therapy and identify …

Selection of the optimal surgical and interventional therapies for advanced colorectal cancer
liver metastases (CRLM) requires multidisciplinary discussion of treatment strategies early in …

Introduction Patients who recur in the first year after resection of colorectal liver metastases
(CRLM) do poorly. The aim of our study was to predict treatment failure in patients …

The liver is a common location of both primary and secondary malignancies. For
unresectable liver cancer, many local ablative therapies have been developed. These …

Background: The crosstalk between cancer cells and stroma is involved in the acquired
capability for metastasis through the induction of epithelial–mesenchymal transition (EMT) …

AIM: To offer an up-to-date review of all available treatment strategies for patients with
synchronous colorectal liver metastases (CLM). METHODS: A comprehensive literature …