Human parvoviruses

J Qiu, M Söderlund-Venermo… - Clinical microbiology …, 2017 - Am Soc Microbiol
SUMMARY Parvovirus B19 (B19V) and human bocavirus 1 (HBoV1), members of the large
Parvoviridae family, are human pathogens responsible for a variety of diseases. For B19V in …

Advances in the development of antiviral strategies against parvovirus B19

E Manaresi, G Gallinella - Viruses, 2019 - mdpi.com
Parvovirus B19 (B19V) is a human pathogenic virus, responsible for an ample range of
clinical manifestations. Infections are usually mild, self-limiting, and controlled by the …

Glycosphingolipid–protein interaction in signal transduction

D Russo, S Parashuraman, G D'Angelo - International Journal of …, 2016 - mdpi.com
Glycosphingolipids (GSLs) are a class of ceramide-based glycolipids essential for embryo
development in mammals. The synthesis of specific GSLs depends on the expression of …

Physicochemical tools for studying virus interactions with targeted cell membranes in a molecular and spatiotemporally resolved context

M Bally, S Block, F Höök, G Larson, N Parveen… - Analytical and …, 2021 - Springer
The objective of this critical review is to provide an overview of how emerging bioanalytical
techniques are expanding our understanding of the complex physicochemical nature of …

Human parvovirus B19 interacts with globoside under acidic conditions as an essential step in endocytic trafficking

J Bieri, R Leisi, C Bircher, C Ros - PLoS pathogens, 2021 - journals.plos.org
The glycosphingolipid (GSL) globoside (Gb4) is essential for parvovirus B19 (B19V)
infection. Historically considered the cellular receptor of B19V, the role of Gb4 and its …

The receptor-binding domain in the VP1u region of parvovirus B19

R Leisi, C Di Tommaso, C Kempf, C Ros - Viruses, 2016 - mdpi.com
Parvovirus B19 (B19V) is known as the human pathogen causing the mild childhood
disease erythema infectiosum. B19V shows an extraordinary narrow tissue tropism for …

Orchestrated efforts on host network hijacking: Processes governing virus replication

X Dai, O Hakizimana, X Zhang, AC Kaushik, J Zhang - Virulence, 2020 - Taylor & Francis
With the high pervasiveness of viral diseases, the battle against viruses has never ceased.
Here we discuss five cellular processes, namely “autophagy”,“programmed cell …

The VP1u receptor restricts parvovirus B19 uptake to permissive erythroid cells

R Leisi, M Von Nordheim, C Ros, C Kempf - Viruses, 2016 - mdpi.com
Parvovirus B19 (B19V) is a small non-enveloped virus and known as the causative agent for
the mild childhood disease erythema infectiosum. B19V has an extraordinary narrow tissue …

Globoside and the mucosal pH mediate parvovirus B19 entry through the epithelial barrier

C Suter, M Colakovic, J Bieri, M Gultom… - PLoS …, 2023 - journals.plos.org
Parvovirus B19 (B19V) is transmitted primarily via the respiratory route, however, the
mechanism involved remains unknown. B19V targets a restricted receptor expressed in …

Globoside is dispensable for parvovirus B19 entry but essential at a postentry step for productive infection

J Bieri, C Ros - Journal of virology, 2019 - Am Soc Microbiol
Globoside (Gb4) is considered the primary receptor of parvovirus B19 (B19V); however, its
expression does not correlate well with the attachment and restricted tropism of the virus …