Significance: Chronic kidney disease (CKD) can be regarded as a burden of lifestyle
disease that shares common underpinning features and risk factors with the aging process; …

During the past 2 decades, results of both basic science and clinical studies have changed
the physicians' views about adipocyte pathophysiology. Since leptin was discovered in …

Results FGF23 correlated directly with IL-6 (r= 0.4), CRP (r= 0.2), TNF-α (r= 0.4), and
fibrinogen (r= 0.3; P< 0.001 for each). In univariate and multivariable-adjusted linear …

Leptin is a small peptide hormone that is mainly, but not exclusively, produced in adipose
tissue. The circulating leptin concentration therefore directly reflects the amount of body fat …

The uremic syndrome is a complex mixture of organ dysfunctions, which is attributed to the
retention of a myriad of compounds that under normal condition are excreted by the healthy …

In the present study, we explore the role of decreased renal function and a genetic
polymorphism on the recently discovered protein resistin, apparently able to inhibit hepatic …

Background: Anorexia is common in chronic kidney disease and worsens as the disease
progresses. Sex hormones and inflammatory cytokines may be related to feeding behavior …

Leptin is a peptide hormone that is mainly, but not exclusively, produced in adipose tissue
and plays a pivotal role in regulating food intake and energy expenditure. Besides its effects …

Objective: To ascertain the relationship between serum leptin levels and related variables
(weight, Body Mass Index (BMI) and fat percentage) in a group of Omani obese and non …

Leptin is an adipocyte-derived hormone that acts as a major regulator of food intake and
energy homeostasis. It circulates both as a free and as a protein-bound entity. Leptin is …