A review on protein markers of exosome from different bio-resources and the antibodies used for characterization

F Deng, J Miller - Journal of Histotechnology, 2019 - Taylor & Francis
Exosomes are small membrane vesicles (ranging from 30 nm to 150 nm), secreted by
different cell types upon fusion of multivesicular bodies (MVB) to the cell plasma membrane …

Blood-based protein biomarkers in bladder urothelial tumors

R López-Cortés, BB Gomez, S Vázquez-Estévez… - Journal of …, 2021 - Elsevier
Bladder cancer (BC) is the fifth most common cancer with a high prevalence rate. It is
classically classified in two groups, namely non-muscle invasive (NMIBC) and muscle …

Relationship between frailty and lower urinary tract symptoms among community‐dwelling adults

O Soma, S Hatakeyama, A Imai… - LUTS: Lower Urinary …, 2020 - Wiley Online Library
Objectives To evaluate the relationship between frailty and lower urinary tract symptoms
(LUTS), the association of frailty and LUTS remains unclear. Methods This cross‐sectional …

Serum N-glycan profiling is a potential biomarker for castration-resistant prostate cancer

T Matsumoto, S Hatakeyama, T Yoneyama… - Scientific Reports, 2019 - nature.com
We investigated the diagnostic and prognostic potential of serum N-glycan profiling for
castration-resistant prostate cancer (CRPC). We retrospectively investigated serum N-glycan …

Aberrant N-Glycosylation Profile of Serum Immunoglobulins is a Diagnostic Biomarker of Urothelial Carcinomas

T Tanaka, T Yoneyama, D Noro, K Imanishi… - International journal of …, 2017 - mdpi.com
The aim of this study to determine whether the aberrant N-glycosylated serum
immunoglobulins (Igs) can be applied as a diagnostic marker of urothelial carcinoma (UC) …

Relationship between oxidative stress and lower urinary tract symptoms: results from a community health survey in Japan

T Matsumoto, S Hatakeyama, A Imai… - BJU …, 2019 - Wiley Online Library
Objective To investigate the relationship between oxidative stress and lower urinary tract
symptoms (LUTS) in a community‐dwelling population. Materials and Methods The cross …

Targeting glycans and heavily glycosylated proteins for tumor imaging

RD Houvast, M Vankemmelbeke, LG Durrant… - Cancers, 2020 - mdpi.com
Simple Summary Distinguishing malignancy from healthy tissue is essential for oncologic
surgery. Targeted imaging during an operation aids the surgeon to operate better. The …

Multicenter prospective study validating the efficacy of a quantitative assessment tool for frailty in patients with urological cancers

O Soma, S Hatakeyama, T Okamoto, N Fujita… - Medical Oncology, 2019 - Springer
We prospectively validate the efficacy of the frailty discriminant score (FDS) in individuals
with urological cancers, as there has been growing importance in evaluating frailty in clinical …

Behavior of blood plasma glycan features in bladder cancer

S Ferdosi, TH Ho, EP Castle, ML Stanton, CR Borges - PloS one, 2018 - journals.plos.org
Despite systemic therapy and cystectomy, bladder cancer is characterized by a high
recurrence rate. Serum glycomics represents a promising source of prognostic markers for …

Machine learning diagnosis by immunoglobulin N‐glycan signatures for precision diagnosis of urological diseases

H Iwamura, K Mizuno, S Akamatsu… - Cancer …, 2022 - Wiley Online Library
Early diagnosis of urological diseases is often difficult due to the lack of specific biomarkers.
More powerful and less invasive biomarkers that can be used simultaneously to identify …