Stimuli-responsive polymers for transdermal, transmucosal and ocular drug delivery

D Berillo, Z Zharkinbekov, Y Kim, K Raziyeva… - Pharmaceutics, 2021 - mdpi.com
Despite their conventional and widespread use, oral and intravenous routes of drug
administration face several limitations. In particular, orally administered drugs undergo …

Flexible Topical Hydrogel Patch Loaded with Antimicrobial Drug for Accelerated Wound Healing

S Saeed, K Barkat, MU Ashraf, M Shabbir, I Anjum… - Gels, 2023 - mdpi.com
A hydrogel topical patch of neomycin was developed by using sodium alginate (SA) and
hydroxyethylcellulose (HEC) as polymers. Free radical polymerization in an aqueous …

Clove oil endorsed transdermal flux of dronedarone hydrochloride loaded bilosomal nanogel: Factorial design, in vitro evaluation and ex vivo permeation

MH Teaima, JM Alsofany, MA El-Nabarawi - AAPS PharmSciTech, 2022 - Springer
The goal of this study was to develop a bilosomal gel formulation to enhance transdermal
permeability of dronedarone hyrdrochloride (DRN) which suffers from poor oral absorption …

Feasibility of enhancing skin permeability of acyclovir through sterile topical lyophilized wafer on self-dissolving microneedle-treated skin

U Nagra, K Barkat, MU Ashraf, M Shabbir - Dose-Response, 2022 - journals.sagepub.com
Acyclovir is an antiviral drug that is frequently prescribed for the herpes virus. However, the
drug requires frequent dosing due to limited bioavailability (10–26.7%). The rationale of the …

Formulation design and development of matrix diffusion controlled transdermal drug delivery of glimepiride

MR Akram, M Ahmad, A Abrar, RM Sarfraz… - Drug design …, 2018 - Taylor & Francis
Background The present work was conducted to prepare and evaluate transdermal patches
with optimization of suitable polymeric blend of poly (meth) acrylates (Eudragit®)(Ammonio …

Development and evaluation of reservoir transdermal polymeric patches for controlled delivery of diclofenac sodium

HM Abdullah, M Farooq, S Adnan, Z Masood… - Polymer Bulletin, 2023 - Springer
The purpose of the study was to prepare a reservoir-controlled transdermal drug delivery
patches containing a diclofenac sodium (DS) as a model drug to achieve a controlled …

Mussel-inspired poly (hydroxyethyl acrylate-co-itaconic acid)-catechol/hyaluronic acid drug-in-adhesive patches for transdermal delivery of ketoprofen

K Arunprasert, C Pornpitchanarong… - International Journal of …, 2022 - Elsevier
This research aimed to create new hydrophilic drug-in-adhesive patches for transdermal
drug delivery. Poly (hydroxyethyl acrylate-co-itaconic acid)-catechol (PHI-cat) and …

[HTML][HTML] Influence of different formulation variables on the performance of transdermal drug delivery system containing tizanidine hydrochloride: in vitro and ex vivo …

M Shabbir, A Sajid, I Hamid, A Sharif… - Brazilian Journal of …, 2019 - SciELO Brasil
The present study was aimed at preparation of transdermal patches of tizanidine HCl,
evaluation of the effect of polymers on in vitro release pattern of the drug, and the effect of …

Assessment of formulation variables of poor water soluble diacerein for its improved loading and anti-inflammatory activity

M Shabbir, K Barkat, MU Ashraf, U Nagra… - Drug Delivery and …, 2023 - Springer
Dissolving microneedles have become a popular method for percutaneous administrationof
drugs. However, loading poorly soluble drugs into water-based dissolving microneedles …

Effect of hydrophilic and hydrophobic polymer on the release of ketoprofen and allopurinol from bilayer matrix transdermal patch

I Arshad, S Ali, U Amin, M Shabbir… - Advances in Polymer …, 2018 - Wiley Online Library
The aim of this study was to design a matrix transdermal patch of ketoprofen and allopurinol
for the possible treatment of arthritis with reduced side effects. For this purpose, a bilayer …