Nucleophosmin is a highly and ubiquitously expressed protein, mainly localized in nucleoli
but able to shuttle between nucleus and cytoplasm. Nucleophosmin plays crucial roles in …

In metal-peptide interactions, cations form stable complexes through bonds with
coordinating groups as side chains of amino acids. These compounds, among other things …

The aggregation of α-synuclein, an intrinsically disordered protein that is highly abundant in
neurons, is closely associated with the onset and progression of Parkinson's disease. We …

The onset and progression of numerous protein misfolding diseases are associated with the
presence of oligomers formed during the aberrant aggregation of several different proteins …

Neurodegenerative diseases are often caused by uncontrolled amyloid aggregation. Hence,
many drug discovery processes are oriented to evaluate new compounds that are able to …

Herein we present a comparative study of the effects of isoquinoline alkaloids belonging to
benzo [c] phenanthridine and berberine families on β-amyloid aggregation. Results …

Herein the effects of three platinum complexes, namely (SP-4-2)-(2, 2′-bipyridine)
dichloridoplatinum (II), Pt-bpy,(SP-4-2)-dichlorido (1, 10-phenanthroline) platinum (II), Pt …

Proteins are widely explored as therapeutic agents, but some issues remain alive in their
delivery versus target tissues and organs. Especially in the case of water-labile proteins …

Background: Nucleopeptides are chimeric compounds of biomedical importance carrying
DNA nucleobases anchored to peptide backbones with the ascertained capacity to bind …

Acute myeloid leukemia (AML) is a clinically and a molecularly heterogeneous disease
characterized by the accumulation of undifferentiated and uncontrolled proliferation of …