Impact of gut microbiome on skin health: gut-skin axis observed through the lenses of therapeutics and skin diseases

MR Mahmud, S Akter, SK Tamanna, L Mazumder… - Gut …, 2022 - Taylor & Francis
The human intestine hosts diverse microbial communities that play a significant role in
maintaining gut-skin homeostasis. When the relationship between gut microbiome and the …

[HTML][HTML] Gut–skin axis: current knowledge of the interrelationship between microbial dysbiosis and skin conditions

B De Pessemier, L Grine, M Debaere, A Maes… - Microorganisms, 2021 - mdpi.com
The microbiome plays an important role in a wide variety of skin disorders. Not only is the
skin microbiome altered, but also surprisingly many skin diseases are accompanied by an …

TREM2 macrophages induced by human lipids drive inflammation in acne lesions

TH Do, F Ma, PR Andrade, R Teles… - Science …, 2022 - science.org
Acne affects 1 in 10 people globally, often resulting in disfigurement. The disease involves
excess production of lipids, particularly squalene, increased growth of Cutibacterium acnes …

What is new in the pathophysiology of acne, an overview

B Dréno - Journal of the European Academy of Dermatology …, 2017 - Wiley Online Library
Acne is a chronic inflammatory disease of the pilosebaceous unit. Its pathophysiology
includes hyperseborrhoea, abnormal follicular keratinization and Propionibacterium acnes …

The epidemiology of acne vulgaris in late adolescence

DD Lynn, T Umari, CA Dunnick… - … health, medicine and …, 2016 - Taylor & Francis
Importance Acne vulgaris is the most common skin condition affecting late adolescents
across the globe. Although prior studies have evaluated epidemiologic patterns of acne …

The gut‐skin axis in health and disease: a paradigm with therapeutic implications

CA O'Neill, G Monteleone, JT McLaughlin, R Paus - Bioessays, 2016 - Wiley Online Library
As crucial interface organs gut and skin have much in common. Therefore it is unsurprising
that several gut pathologies have skin co‐morbidities. Nevertheless, the reason for this …

Acne vulgaris

SM Tuchayi, E Makrantonaki, R Ganceviciene… - Nature reviews Disease …, 2015 - nature.com
Acne vulgaris is a chronic inflammatory disease—rather than a natural part of the life cycle
as colloquially viewed—of the pilosebaceous unit (comprising the hair follicle, hair shaft and …

[HTML][HTML] Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C (ut) annabinoid” System

KF Tóth, D Ádám, T Bíró, A Oláh - Molecules, 2019 - mdpi.com
The endocannabinoid system (ECS) has lately been proven to be an important, multifaceted
homeostatic regulator, which influences a wide-variety of physiological processes all over …

[HTML][HTML] Skin lipids in health and disease: A review

S Knox, NM O'Boyle - Chemistry and physics of lipids, 2021 - Elsevier
Our skin is the interface between us and our environment–a flexible barrier that has evolved
for protection, immunity, regulation and sensation. Once regarded as inert, we now know …

[HTML][HTML] Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes

A Oláh, BI Tóth, I Borbíró, K Sugawara… - The Journal of …, 2014 - Am Soc Clin Investig
The endocannabinoid system (ECS) regulates multiple physiological processes, including
cutaneous cell growth and differentiation. Here, we explored the effects of the major …