In recent years, DNA has emerged as a fascinating building material to engineer hydrogel
due to its excellent programmability, which has gained considerable attention in biomedical …

Background Biocompatible smart materials have ushered in revolutionary applications,
conferring significant benefits upon humanity. Among these materials, DNA hydrogels stand …

Sequence-encoded biomolecules such as DNA and peptides are powerful programmable
building blocks for nanomaterials. This paradigm is enabled by decades of prior research …

External stimuli-responsive DNA hydrogels present interesting platforms for drug loading
and triggered release. Typically, drug molecules are encapsulated within three …

DNA and RNA nanostructures are being investigated as therapeutics, vaccines, and drug
delivery systems. These nanostructures can be functionalized with guests ranging from …

Tension gauge tethers (TGTs), short DNA segments serving as extracellular tension
sensors, are instrumental in assessing the tension dynamics in mechanotransduction. These …

With the advent of DNA nanotechnology, DNA-based biomaterials have emerged as a
unique class of materials at the center of various biological advances. Owing to DNA's high …

Excessive cell‐free DNA (cfDNA) can induce chronic inflammation by activating intracellular
nucleic acid sensors. Intervention in cfDNA‐mediated “pro‐inflammatory signaling …

Expanding the functions and applications of DNA by integrating noncanonical bases and
structures into biopolymers is a continuous scientific effort. An adenine-rich strand (A-strand) …

The arbitrary, modular, and reprogrammable engineering of macroscopic objects by DNA
interactions remains a challenge, despite the well-established use of DNA to drive …