Burden of illness in people with Alzheimer's disease: a systematic review of epidemiology, comorbidities and mortality
KL Lanctôt, JH Hahn-Pedersen, CS Eichinger… - The Journal of …, 2024 - Springer
Background Alzheimer's disease (AD) is the most common neurodegenerative disease
worldwide, and an updated quantification of its impact on morbidity, disability, and mortality …
worldwide, and an updated quantification of its impact on morbidity, disability, and mortality …
The relationship between midlife dyslipidemia and lifetime incidence of dementia: A systematic review and meta‐analysis of cohort studies
J Wee, S Sukudom, S Bhat, M Marklund… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction We conducted a systematic review and meta‐analysis to review the relationship
between midlife dyslipidemia and lifetime incident dementia. Methods The databases …
between midlife dyslipidemia and lifetime incident dementia. Methods The databases …
Association of systolic blood pressure with dementia risk and the role of age, U-shaped associations, and mortality
Importance The optimal systolic blood pressure (SBP) to minimize the risk of dementia in
older age is unknown. Objective To investigate whether the association between SBP and …
older age is unknown. Objective To investigate whether the association between SBP and …
Hypertension and hyperhomocysteinemia as modifiable risk factors for Alzheimer's disease and dementia: New evidence, potential therapeutic strategies, and …
This review summarizes recent evidence on how mid‐life hypertension,
hyperhomocysteinemia (HHcy) and blood pressure variability, as well as late‐life …
hyperhomocysteinemia (HHcy) and blood pressure variability, as well as late‐life …
Sex differences in risk factors for incident peripheral artery disease hospitalisation or death: Cohort study of UK Biobank participants
Background Women with peripheral artery disease (PAD) often have atypical symptoms, late
hospital presentations, and worse prognosis. Risk factor identification and management are …
hospital presentations, and worse prognosis. Risk factor identification and management are …
Sex differences in the association between cardiovascular diseases and dementia subtypes: a prospective analysis of 464,616 UK Biobank participants
C Dong, C Zhou, C Fu, W Hao, A Ozaki… - Biology of sex …, 2022 - Springer
Background Whether the association of cardiovascular diseases (CVDs) with dementia
differs by sex remains unclear, and the role of socioeconomic, lifestyle, genetic, and medical …
differs by sex remains unclear, and the role of socioeconomic, lifestyle, genetic, and medical …
South Asian, Black and White ethnicity and the effect of potentially modifiable risk factors for dementia: A study in English electronic health records
Introduction We aimed to investigate ethnic differences in the associations of potentially
modifiable risk factors with dementia. Methods We used anonymised data from English …
modifiable risk factors with dementia. Methods We used anonymised data from English …
Diastolic blood pressure and intensive blood pressure control on cognitive outcomes: insights from the SPRINT MIND trial
C Jiang, S Li, Y Wang, Y Lai, Y Bai, M Zhao, L He… - …, 2023 - Am Heart Assoc
Background: The potential benefits or harms of intensive systolic blood pressure (BP) control
on cognitive function and cerebral blood flow in individuals with low diastolic blood pressure …
on cognitive function and cerebral blood flow in individuals with low diastolic blood pressure …
Associations of resting heart rate with incident dementia, cognition, and brain structure: a prospective cohort study of UK biobank
YT Deng, K Kuo, BS Wu, YN Ou, L Yang… - Alzheimer's Research & …, 2022 - Springer
Background Resting heart rate (RHR) has been linked with an increased risk of dementia.
However, evidence characterizing the associations of RHR with different dementia subtypes …
However, evidence characterizing the associations of RHR with different dementia subtypes …
Neuron-level explainable AI for Alzheimer's Disease assessment from fundus images
N Yousefzadeh, C Tran, A Ramirez-Zamora, J Chen… - Scientific Reports, 2024 - nature.com
Alzheimer's Disease (AD) is a progressive neurodegenerative disease and the leading
cause of dementia. Early diagnosis is critical for patients to benefit from potential intervention …
cause of dementia. Early diagnosis is critical for patients to benefit from potential intervention …