Mitochondria as a cellular hub in infection and inflammation

P Andrieux, C Chevillard, E Cunha-Neto… - International journal of …, 2021 - mdpi.com
Mitochondria are the energy center of the cell. They are found in the cell cytoplasm as
dynamic networks where they adapt energy production based on the cell's needs. They are …

Bridging biological cfDNA features and machine learning approaches

T Moser, S Kühberger, I Lazzeri, G Vlachos, E Heitzer - Trends in Genetics, 2023 - cell.com
Liquid biopsies (LBs), particularly using circulating tumor DNA (ctDNA), are expected to
revolutionize precision oncology and blood-based cancer screening. Recent technological …

Postural orthostatic tachycardia syndrome as a sequela of COVID-19

CK Ormiston, I Świątkiewicz, PR Taub - Heart Rhythm, 2022 - Elsevier
Postural orthostatic tachycardia syndrome (POTS) is a complex multisystem disorder
characterized by orthostatic intolerance and tachycardia and may be triggered by viral …

Possible pathogenesis and prevention of long COVID: SARS-CoV-2-induced mitochondrial disorder

TH Chen, CJ Chang, PH Hung - International journal of molecular …, 2023 - mdpi.com
Patients who have recovered from coronavirus disease 2019 (COVID-19) infection may
experience chronic fatigue when exercising, despite no obvious heart or lung abnormalities …

Detecting cell-of-origin and cancer-specific methylation features of cell-free DNA from Nanopore sequencing

E Katsman, S Orlanski, F Martignano, I Fox-Fisher… - Genome Biology, 2022 - Springer
Abstract The Oxford Nanopore (ONT) platform provides portable and rapid genome
sequencing, and its ability to natively profile DNA methylation without complex sample …

Cell-free DNA-based liquid biopsies in neurology

H Gaitsch, RJM Franklin, DS Reich - Brain, 2023 - academic.oup.com
This article reviews recent developments in the application of cell-free DNA-based liquid
biopsies to neurological diseases. Over the past few decades, an explosion of interest in the …

NSP4 and ORF9b of SARS-CoV-2 induce pro-inflammatory mitochondrial DNA release in inner membrane-derived vesicles

MI Faizan, R Chaudhuri, S Sagar, S Albogami… - Cells, 2022 - mdpi.com
Circulating cell-free mitochondrial DNA (cf-mtDNA) has been found in the plasma of
severely ill COVID-19 patients and is now known as a strong predictor of mortality. However …

[HTML][HTML] COVID-19 induced postural orthostatic tachycardia syndrome (POTS): a review

D Mallick, L Goyal, P Chourasia, MR Zapata, K Yashi… - Cureus, 2023 - ncbi.nlm.nih.gov
Abstract POTS (Postural Orthostatic Tachycardia Syndrome) is a multisystem disorder
characterized by the abnormal autonomic response to an upright posture, causing …

Cigarette smoke induces mitochondrial DNA damage and activates cGAS-STING pathway: application to a biomarker for atherosclerosis

K Ueda, C Sakai, T Ishida, K Morita… - Clinical …, 2023 - portlandpress.com
Cigarette smoking is a major risk factor for atherosclerosis. We previously reported that DNA
damage was accumulated in atherosclerotic plaque, and was increased in human …

Cell-free DNA as diagnostic and prognostic biomarkers for adult sepsis: a systematic review and meta-analysis

A Charoensappakit, K Sae-Khow, P Rattanaliam… - Scientific Reports, 2023 - nature.com
Although cell-free DNA (cfDNA) is an emerging sepsis biomarker, the use of cfDNA,
especially as diagnostic and prognostic indicators, has surprisingly not been systemically …