Nanopore-based sensors have established themselves as a prominent tool for solution-
based, single-molecule analysis of the key building blocks of life, including nucleic acids …

Biotechnological innovations have vastly improved the capacity to perform large-scale
protein studies, while the methods we have for identifying and quantifying individual proteins …

Established methods for characterizing proteins typically require physical or chemical
modification steps or cannot be used to examine individual molecules in solution. Ionic …

Solid-state nanopores are nm sized apertures formed in thin synthetic membranes. These
single molecule sensors have been used in a variety of biophysical and diagnostic …

Nanopores exhibit a set of interesting transport properties that stem from interactions of the
passing ions and molecules with the pore walls. Nanopores are used, for example, as ionic …

Much more than ever, nucleic acids are recognized as key building blocks in many of lifeʼs
processes, and the science of studying these molecular wonders at the single-molecule …

Nanopore systems have emerged as a leading platform for the analysis of biomolecular
complexes with single-molecule resolution. The conformation of biomolecules, such as …

Synthetic nanopores have been used to study individual biomolecules in high throughput,
but their performance as sensors does not match that of biological ion channels. Challenges …

The solid‐state nanopore has attracted much attention as a next‐generation DNA
sequencing tool or a single‐molecule biosensor platform with its high sensitivity of …

In nanopore analytics, individual molecules pass through a single nanopore giving rise to
detectable temporary blockades in ionic pore current. Reflecting its simplicity, nanopore …