Tandem NBPF 3mer HORs (Olduvai triplets) in Neanderthal and two novel HOR tandem arrays in human chromosome 1 T2T-CHM13 assembly

M Glunčić, I Vlahović, M Rosandić, V Paar - Scientific Reports, 2023 - nature.com
It is known that the~ 1.6 kb Neuroblastoma BreakPoint Family (NBPF) repeats are human
specific and contributing to cognitive capabilities, with increasing frequency in higher order …

NBPF1, a tumor suppressor candidate in neuroblastoma, exerts growth inhibitory effects by inducing a G1 cell cycle arrest

V Andries, K Vandepoele, K Staes, G Berx, P Bogaert… - BMC cancer, 2015 - Springer
Abstract Background NBPF1 (Neuroblastoma Breakpoint Family, member 1) was originally
identified in a neuroblastoma patient on the basis of its disruption by a chromosomal …

Tandemly repeated NBPF HOR copies (Olduvai triplets): Possible impact on human brain evolution

M Glunčić, I Vlahović, M Rosandić… - Life science …, 2023 - life-science-alliance.org
Previously it was found that the neuroblastoma breakpoint family (NBPF) gene repeat units
of∼ 1.6 kb have an important role in human brain evolution and function. The higher order …

[HTML][HTML] Tumor-suppressor gene NBPF1 inhibits invasion and PI3K/mTOR signaling in cervical cancer cells

Y Qin, X Tang, M Liu - Oncology research, 2016 - ncbi.nlm.nih.gov
The purpose of this study was to assess the effects of NBPF1 expression on cervical cancer
cell invasion and apoptosis and to illustrate its potential mechanism. Human cervical cancer …

A genome-wide association study for melatonin secretion

PH Liu, GT Chuang, CN Hsiung, WS Yang, HC Ku… - Scientific Reports, 2022 - nature.com
Melatonin exerts a wide range of effects among various tissues and organs. However, there
is currently no study to investigate the genetic determinants of melatonin secretion. Here, we …

The N-terminal of NBPF15 causes multiple types of aggregates and mediates phase transition

H Wu, LT Zhai, XX Guo, S Rety, XG Xi - Biochemical Journal, 2020 - portlandpress.com
The neuroblastoma breakpoint family (NBPF) consists of 24 members that play an important
role in neuroblastoma and other cancers. NBPF is an evolutionarily recent gene family that …

Global Repeat Map (GRM): advantageous method for discovery of largest Higher-Order Repeats (HORs) in Neuroblastoma Breakpoint Family (NBPF) genes, in …

V Paar, I Vlahović, M Rosandić, M Glunčić - Satellite DNAs in Physiology …, 2021 - Springer
Here we present three interesting novel human Higher-Order Repeats (HORs) discovered
using the HOR-searching method with GRM algorithm:(a) The novel Neuroblastoma …

Tandemly repeated NBPF 3mer HOR copies (Olduvai triplets) in Neanderthal AltaiNea. hg19 assembly and two novel tandem arrays of NBPF 3mer HOR repeats in …

M Glunčić, I Vlahović, M Rosandić, V Paar - bioRxiv, 2023 - biorxiv.org
It is known that the∼ 1.6 kb NBPF repeats are human specific and contributing to cognitive
capabilities, with increasing frequency in higher order repeat 3mer HORs (Olduvai triplets) …

[HTML][HTML] Metagenomic analysis of viral genes integrated in whole genome sequencing data of Thai patients with Brugada syndrome

S Chitcharoen, C Phokaew… - Genomics & …, 2022 - ncbi.nlm.nih.gov
Brugada syndrome (BS) is an autosomal dominant inheritance cardiac arrhythmia disorder
associated with sudden death in young adults. Thailand has the highest prevalence of BS …

Futuros que están siendo. Investigación-creación por los senderos de luchas autónomas y comunitarias en América Latina

R Gómez, D Rebeca, G Makaran, B Márquez… - 2023 - librosoa.unam.mx
Si bien el presente libro electrónico e interactivo es resultado del Proyecto PAPIIT
Autonomía vs. Hegemonía. Estado latinoamericano y emancipación social desde los …