Organisms evolve in response to their natural environment. Consideration of natural
ecological parameters are thus of key importance for our understanding of an organism's …

Iron is an essential nutrient for both humans and pathogenic microbes. Because of its ability
to exist in one of two oxidation states, iron is an ideal redox catalyst for diverse cellular …

Most Caenorhabditis elegans studies have used laboratory Escherichia coli as diet and
microbial environment. Here we characterize bacteria of C. elegans' natural habitats of …

Iron is an essential nutrient for life. During infection, a fierce battle of iron acquisition occurs
between the host and bacterial pathogens. Bacteria acquire iron by secreting siderophores …

Iron is an essential element for all microorganisms. Siderophores are low-weight, high-
affinity iron chelating molecules produced in response to iron deficiency by Gram-positive …

Metazoans identify and eliminate bacterial pathogens in microbe-rich environments such as
the intestinal lumen; however, the mechanisms are unclear. Host cells could potentially use …

Plant-parasitic nematodes cause significant damage to a broad range of vegetables and
agricultural crops throughout the world. As the natural enemies of nematodes …

Redox signalling in the gastrointestinal mucosa is held in an intricate balance. Potent
microbicidal mechanisms can be used by infiltrating immune cells, such as neutrophils, to …

Elucidating the benefits of individual microbiota-derived molecules in host animals is
important for understanding the symbiosis between humans and their microbiota. The …

Caenorhabditis elegans is an important model organism with many useful features,
including rapid development and aging, easy cultivation, and genetic tractability. Survival …