Gangliosides are glycosphingolipids highly abundant in the nervous system, and carry most
of the sialic acid residues in the brain. Gangliosides are enriched in cell membrane …

Every cell in nature carries a rich surface coat of glycans, its glycocalyx, which constitutes
the cell's interface with its environment. In eukaryotes, the glycocalyx is composed of …

Simple and complex carbohydrates (glycans) have long been known to play major
metabolic, structural and physical roles in biological systems. Targeted microbial binding to …

Virus–receptor interactions play a key regulatory role in viral host range, tissue tropism, and
viral pathogenesis. Viruses utilize elegant strategies to attach to one or multiple receptors …

Gangliosides are structurally and functionally polymorphic sialic acid containing
glycosphingolipids that are widely distributed in the human body. They play important roles …

Sphingolipids are highly enriched in the nervous system where they are pivotal constituents
of the plasma membranes and are important for proper brain development and functions …

Much has been made about JLW Thudichum's colorful, and one could say clairvoyant,
naming of sphingosine “in commemoration of the many enigmas which it presented to the …

Glycosylation produces an abundant, diverse, and highly regulated repertoire of cellular
glycans that are frequently attached to proteins and lipids. The past decade of research on …

The surfaces of all vertebrate cells are decorated with a dense and complex array of sugar
chains, which are mostly attached to proteins and lipids. Most soluble secreted proteins are …

Gangliosides are sialic acid-containing glycosphingolipids that are most abundant in the
nervous system. Heterogeneity and diversity of the structures in their carbohydrate chains …