Recent developments in two-dimensional liquid chromatography: fundamental improvements for practical applications

BWJ Pirok, DR Stoll, PJ Schoenmakers - Analytical Chemistry, 2018 - ACS Publications
Liquid chromatography (LC) is an incredibly successful analytical separation tool. Its
versatility is unprecedented because of the many different separation modes …

Tutorial on lipidomics

J Wang, C Wang, X Han - Analytica chimica acta, 2019 - Elsevier
The mainstream of lipidomics involves mass spectrometry-based, systematic, and large-
scale studies of the structure, composition, and quantity of lipids in biological systems such …

Identification of urinary metabolites that correlate with clinical improvements in children with autism treated with sulforaphane from broccoli

S Bent, B Lawton, T Warren, F Widjaja, K Dang… - Molecular autism, 2018 - Springer
Background Children with autism spectrum disorder (ASD) have urinary metabolites
suggesting impairments in several pathways, including oxidative stress, inflammation …

Strategies to circumvent the solvent strength mismatch problem in online comprehensive two‐dimensional liquid chromatography

S Chapel, S Heinisch - Journal of Separation Science, 2022 - Wiley Online Library
On‐line comprehensive two‐dimensional liquid chromatography is a powerful technique for
the separation of highly complex samples. Due to the addition of the second dimension of …

[HTML][HTML] Neurolipidomic insights into anxiety disorders: Uncovering lipid dynamics for potential therapeutic advances

S Maehashi, K Arora, AL Fisher, DR Schweitzer… - Neuroscience & …, 2024 - Elsevier
Anxiety disorders constitute a spectrum of psychological conditions affecting millions of
individuals worldwide, imposing a significant health burden. Historically, the development of …

Multidimensional liquid chromatography-mass spectrometry for metabolomic and lipidomic analyses

W Lv, X Shi, S Wang, G Xu - TrAC Trends in Analytical Chemistry, 2019 - Elsevier
As important components of omics, metabolomics and lipidomics are dedicated to detecting
as many metabolites and lipids as possible, respectively, in biological samples. Because the …

Evaluation of a Liquid Chromatography–Tandem Mass Spectrometry Method for the Analysis of Glucosylceramide and Galactosylceramide Isoforms in Cerebrospinal …

L Castillo-Ribelles, JA Arranz-Amo… - Analytical …, 2024 - ACS Publications
Mutations in GBA1, encoding glucocerebrosidase beta 1 (GCase), are the most common
genetic risk factor for Parkinson's disease (PD). GCase dysfunction leads to an accumulation …

Rapid profiling method for the analysis of lipids in human plasma using ion mobility enabled-reversed phase-ultra high performance liquid chromatography/mass …

AM King, RD Trengove, LG Mullin, PD Rainville… - … of chromatography A, 2020 - Elsevier
The incorporation of ion mobility (IM) into LC–MS analysis has been demonstrated to result
in the generation of superior quality MS and MS/MS spectral data as well as providing …

Pushing the limits of resolving power and analysis time in on-line comprehensive hydrophilic interaction x reversed phase liquid chromatography for the analysis of …

S Chapel, F Rouvière, S Heinisch - Journal of Chromatography A, 2020 - Elsevier
In the present work, we have investigated the combination of hydrophilic interaction liquid
chromatography (HILIC) and reversed phase liquid chromatography (RPLC) for the …

Plasmalogens-ubiquitous molecules occurring widely, from anaerobic bacteria to humans

M Vitova, A Palyzová, T Řezanka - Progress in Lipid Research, 2021 - Elsevier
Plasmalogens are a group of lipids mainly found in the cell membranes. They occur in
anaerobic bacteria and in some protozoa, invertebrates and vertebrates, including humans …