Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2021 - Wiley Online Library
The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

[HTML][HTML] Current status and perspectives in translational biomarker research for PD-1/PD-L1 immune checkpoint blockade therapy

W Ma, BM Gilligan, J Yuan, T Li - Journal of hematology & oncology, 2016 - Springer
Modulating immune inhibitory pathways has been a major recent breakthrough in cancer
treatment. Checkpoint blockade antibodies targeting cytotoxic T-lymphocyte antigen 4 …

Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials

B Sawitzki, PN Harden, P Reinke, A Moreau… - The Lancet, 2020 - thelancet.com
Background Use of cell-based medicinal products (CBMPs) represents a state-of-the-art
approach for reducing general immunosuppression in organ transplantation. We tested …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

Guidelines for the use of flow cytometry and cell sorting in immunological studies*

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2017 - Wiley Online Library
From a technical point of view a flow cytometer is a light detection device capable of
detecting photons of different wavelengths over a high dynamic range. In order to achieve a …

Regulatory T cells for minimising immune suppression in kidney transplantation: phase I/IIa clinical trial

A Roemhild, NM Otto, G Moll, M Abou-El-Enein… - bmj, 2020 - bmj.com
Objective To assess whether reshaping of the immune balance by infusion of autologous
natural regulatory T cells (nTregs) in patients after kidney transplantation is safe, feasible …

Applicability, safety, and biological activity of regulatory T cell therapy in liver transplantation

A Sánchez‐Fueyo, G Whitehouse… - American Journal of …, 2020 - Wiley Online Library
Regulatory T cells (Tregs) are a lymphocyte subset with intrinsic immunosuppressive
properties that can be expanded in large numbers ex vivo and have been shown to prevent …

[HTML][HTML] Standardizing flow cytometry immunophenotyping analysis from the human immunophenotyping consortium

G Finak, M Langweiler, M Jaimes, M Malek… - Scientific reports, 2016 - nature.com
Standardization of immunophenotyping requires careful attention to reagents, sample
handling, instrument setup, and data analysis, and is essential for successful cross-study …

[HTML][HTML] Novel technologies and emerging biomarkers for personalized cancer immunotherapy

J Yuan, PS Hegde, R Clynes, PG Foukas… - … for immunotherapy of …, 2016 - Springer
The culmination of over a century's work to understand the role of the immune system in
tumor control has led to the recent advances in cancer immunotherapies that have resulted …

Feasibility, long‐term safety, and immune monitoring of regulatory T cell therapy in living donor kidney transplant recipients

PN Harden, DS Game, B Sawitzki… - American Journal of …, 2021 - Wiley Online Library
Short‐term outcomes in kidney transplantation are marred by progressive transplant failure
and mortality secondary to immunosuppression toxicity. Immune modulation with autologous …