Biological glass: structural determinants of eye lens transparency

S Bassnett, Y Shi… - … Transactions of the …, 2011 - royalsocietypublishing.org
The purpose of the lens is to project a sharply focused, undistorted image of the visual
surround onto the neural retina. The first pre-requisite, therefore, is that the tissue should be …

Apoptosis in lens development and pathology

Q Yan, JP Liu, D Wan‐Cheng Li - Differentiation, 2006 - Wiley Online Library
The ocular lens is a distinct system to study cell death for the following reasons. First, during
animal development, the ocular lens is crafted into its unique shape. The crafting processes …

Human αA-and αB-crystallins prevent UVA-induced apoptosis through regulation of PKCα, RAF/MEK/ERK and AKT signaling pathways

JP Liu, R Schlosser, WY Ma, Z Dong, H Feng… - Experimental eye …, 2004 - Elsevier
αA-and αB-crystallins are distinct antiapoptotic regulators. Regarding the antiapoptotic
mechanisms, we have previously demonstrated that under staurosporine treatment, HαA …

[HTML][HTML] Influence of exposure time for UV radiation–induced cataract

MN Ayala, R Michael… - … ophthalmology & visual …, 2000 - arvojournals.org
purpose. It is believed that for a certain ultraviolet radiation (UVR) exposure, the biologic
effect depends on the product of irradiance and exposure time (the reciprocity Bunsen …

Ultraviolet radiation and the eye

MS Oliva, H Taylor - International ophthalmology clinics, 2005 - journals.lww.com
Moderate exposure to ultraviolet radiation (UVR) from the sun is a necessary part of
maintaining normal health. Ultraviolet radiation is critical for formation of Vitamin D and the …

Cataract formation mechanisms and risk in aviation and space crews

JA Jones, M McCarten, K Manuel… - Aviation, space, and …, 2007 - ingentaconnect.com
Jones JA, McCarten M, Manuel K, Djojonegoro B, Murray J, Feiversen A, Wear M. Cataract
formation mechanisms and risk in aviation and space crews. Aviat Space Environ Med 2007; …

Cataract formation in a strain of rats selected for high oxidative stress

S Marsili, RI Salganik, CD Albright, CD Freel… - Experimental eye …, 2004 - Elsevier
The primary purpose of this study was to define the clinical and morphological features of
cataractogenesis in the OXYS strain of rats that generate excess reactive oxygen species …

Induction of matrix metalloproteinases 2 and 9 following stress to the lens

S Tamiya, IM Wormstone, JM Marcantonio… - Experimental eye …, 2000 - Elsevier
Matrix metalloproteinase 2 and 9 (MMP-2 and 9, also known as gelatinase A and B) have
been implicated in a number of eye diseases, but their possible involvement in lens …

Homeostasis in the vertebrate lens: mechanisms of solute exchange

R Dahm, J van Marle, RA Quinlan… - … of the Royal …, 2011 - royalsocietypublishing.org
The eye lens is avascular, deriving nutrients from the aqueous and vitreous humours. It is,
however, unclear which mechanisms mediate the transfer of solutes between these …

Lens epithelial apoptosis and cell proliferation in human age-related cortical cataract

A Charakidas, A Kalogeraki… - European journal of …, 2005 - journals.sagepub.com
Purpose To probe the presence of apoptosis in the epithelium of human lenses with age-
related cortical cataract as well as to assess cell proliferation, a predicted consequence of …