Molecular toxicology of sulfur mustard-induced cutaneous inflammation and blistering
K Kehe, F Balszuweit, D Steinritz, H Thiermann - Toxicology, 2009 - Elsevier
Sulfur mustard (SM) is a strong alkylating agent, which produces subepidermal blisters,
erythema and inflammation after skin contact. Despite the well-described SM-induced gross …
erythema and inflammation after skin contact. Despite the well-described SM-induced gross …
The biological functions, structure and sources of CXCL10 and its outstanding part in the pathophysiology of multiple sclerosis
The etiology of several autoimmune diseases, including multiple sclerosis (MS), has still not
been completely clarified. MS is defined as an autoimmune disease with clinical features of …
been completely clarified. MS is defined as an autoimmune disease with clinical features of …
Inhibitory Effect of Centella asiatica Extract on DNCB-Induced Atopic Dermatitis in HaCaT Cells and BALB/c Mice
Atopic dermatitis (AD) is a chronic inflammatory skin disease caused mainly by immune
dysregulation. This study explored the anti-inflammatory and immunomodulatory effects of …
dysregulation. This study explored the anti-inflammatory and immunomodulatory effects of …
Sulfur mustard toxicity: history, chemistry, pharmacokinetics, and pharmacodynamics
Sulfur mustard (SM) and similar bifunctional agents have been used as chemical weapons
for almost 100 years. Victims of high-dose exposure, both combatants and civilians, may die …
for almost 100 years. Victims of high-dose exposure, both combatants and civilians, may die …
Vitamin D3 ameliorates nitrogen mustard‐induced cutaneous inflammation by inactivating the NLRP3 inflammasome through the SIRT3–SOD2–mtROS signaling …
X Dong, Y He, F Ye, Y Zhao, J Cheng… - Clinical and …, 2021 - Wiley Online Library
Nitrogen mustard (NM) causes severe skin injury with an obvious inflammatory response,
which is lack of effective and targeted therapies. Vitamin D3 (VD3) has excellent anti …
which is lack of effective and targeted therapies. Vitamin D3 (VD3) has excellent anti …
Role of inflammation and oxidative stress in chemotherapy-induced neurotoxicity
Chemotherapeutic agents may adversely affect the nervous system, including the neural
precursor cells as well as the white matter. Although the mechanisms are not completely …
precursor cells as well as the white matter. Although the mechanisms are not completely …
[HTML][HTML] Sulfur mustard research—strategies for the development of improved medical therapy
K Kehe, F Balszuweit, J Emmler, H Kreppel, M Jochum… - Eplasty, 2008 - ncbi.nlm.nih.gov
Objective: Sulfur mustard (SM) is a bifunctional alkylating substance being used as chemical
warfare agent (vesicant). It is still regarded as a significant threat in chemical warfare and …
warfare agent (vesicant). It is still regarded as a significant threat in chemical warfare and …
Nitrogen mustard exposure of murine skin induces DNA damage, oxidative stress and activation of MAPK/Akt-AP1 pathway leading to induction of inflammatory and …
D Kumar, N Tewari-Singh, C Agarwal, AK Jain, S Inturi… - Toxicology letters, 2015 - Elsevier
Our recent studies in SKH-1 hairless mice have demonstrated that topical exposure to
nitrogen mustard (NM), an analog of sulfur mustard (SM), triggers the inflammatory …
nitrogen mustard (NM), an analog of sulfur mustard (SM), triggers the inflammatory …
Eckol from Ecklonia cava ameliorates TNF-α/IFN-γ-induced inflammatory responses via regulating MAPKs and NF-κB signaling pathway in HaCaT cells
SH Cho, HS Kim, WW Lee, EJ Han, SY Kim… - International …, 2020 - Elsevier
We investigated the protective effect of the bioactive compound eckol on inflammatory-
related skin lesions in vitro. HaCaT cells were stimulated with tumor necrosis factor-alpha …
related skin lesions in vitro. HaCaT cells were stimulated with tumor necrosis factor-alpha …
Effect of peiminine on DNCB-induced atopic dermatitis by inhibiting inflammatory cytokine expression in vivo and in vitro
JM Lim, B Lee, JH Min, EY Kim, JH Kim… - International …, 2018 - Elsevier
Peiminine (PMN) is the main component derived from Fritillaria ussuriensis and is used in
traditional medicine in East Asia. The aim of this study was to evaluate the effects of PMN on …
traditional medicine in East Asia. The aim of this study was to evaluate the effects of PMN on …