Disease registries have traditionally been vehicles for the collection of clinical data, in most
instances following a large number of patients for a long time period in an observational …

Background Prospective cohort studies have made enormous contributions to our
understanding of coronary heart disease (CHD) epidemiology in the UK. However …

Coronary Heart Disease (CHD) death rates have fallen considerably in many countries. We
estimated the life-years-gained (LYG) in Scotland between 1975 and 1994 attributable to …

Left ventricular hypertrophy in patients with hypertension is a main clinical prognostic entity.
The aim of this study was to evaluate the association between mutations at genes of the …

Smoking is the single biggest cause of preventable death in the Uited Kingdom (UK) and is
a major cause of coronary heart disease, some cancers, and respiratory disease, including …

Background: Although the preferred management of a patient presenting with an acute
myocardial infarction is in a coronary care unit, data based on discharge diagnoses in Israel …

Introduction: Resource allocation at a local level involves making difficult decisions about
investment and, particularly in a time of economic stringency, about disinvestment. These …

Background. Mortality from cardiovascular diseases (CVD) has declined substantially in the
US during the past several decades. However, it is not certain to what extent the decline in …

In Chapter 1, the challenges of conducting evaluations in biomedical informatics were
introduced, and the specific sources of complexity that give rise to these challenges were …