Spherical crystallization of drugs

B Kovačič, F Vrečer, O Planinšek - Acta pharmaceutica, 2012 - sciendo.com
Spherical crystallization of drugs is the process of obtaining larger particles by
agglomeration during crystallization. The most common techniques used to obtain such …

Curcumin nanoparticles improve the physicochemical properties of curcumin and effectively enhance its antioxidant and antihepatoma activities

FL Yen, TH Wu, CW Tzeng, LT Lin… - Journal of agricultural …, 2010 - ACS Publications
Curcumin (CUR), a natural polyphenol isolated from tumeric (Curcuma longa), has been
documented to possess antioxidant and anticancer activities. Unfortunately, the compound …

Crystal engineering for enhanced solubility and bioavailability of poorly soluble drugs

J Varshosaz, E Ghassami… - Current pharmaceutical …, 2018 - ingentaconnect.com
Background: Crystal engineering is dealing with the creation of new structures and new
properties in drug molecules through inter-molecular interactions. Researchers of …

[PDF][PDF] Mechanism of dissolution enhancement and bioavailability of poorly water soluble celecoxib by preparing stable amorphous nanoparticles

Y Liu, C Sun, Y Hao, T Jiang… - Journal of pharmacy …, 2010 - frontierspartnerships.org
Purpose: Nanoparticle engineering offers promising methods for the formulation of poorly
water soluble drug compounds. The aim of the present work was to enhance dissolution and …

Silica-lipid hybrid (SLH) microcapsules: a novel oral delivery system for poorly soluble drugs

A Tan, S Simovic, AK Davey, T Rades… - Journal of controlled …, 2009 - Elsevier
A silica-lipid hybrid (SLH) microcapsule system for oral delivery of poorly water-soluble
drugs is reported for the first time. For the model drug celecoxib (CEL), SLH microcapsules …

Solubility enhancement of BCS Class II drug by solid phospholipid dispersions: Spray drying versus freeze-drying

SYK Fong, A Ibisogly, A Bauer-Brandl - International journal of …, 2015 - Elsevier
The poor aqueous solubility of BCS Class II drugs represents a major challenge for oral
dosage form development. Using celecoxib (CXB) as model drug, the current study adopted …

[PDF][PDF] Formulation and evaluation of etoricoxib niosomes by thin film hydration technique and ether injection method

V Ravalika, AK Sailaja - Nano Biomed Eng, 2017 - researchgate.net
The main objective of this study is to formulate etoricoxib niosomes as vesicular carriers for
site specific drug delivery. Niosomes are novel vesicular carriers, in which the drug is …

Enabling the drug combination of celecoxib through a spherical co-agglomeration strategy with controllable and stable drug content and good powder properties

S Guo, C Yu, S Feng, J Wei, L Tong, K Li, Y Gao… - International Journal of …, 2022 - Elsevier
Combining celecoxib with other chemopreventive drugs is a promising method of
chemoprevention for cancer, especially for colorectal cancer. However, the traditional drug …

In Vitro and In Vivo Evaluation of Proniosomes Containing Celecoxib for Oral Administration

M Nasr - Aaps Pharmscitech, 2010 - Springer
The objectives of this research were to prepare celecoxib proniosomes and evaluate the
influence of proniosomal formulation on the oral bioavailability of the drug in human …

Spherical agglomerates of lactose with enhanced mechanical properties

D Lamešić, O Planinšek, Z Lavrič, I Ilić - International journal of …, 2017 - Elsevier
The aim of this study was to prepare spherical agglomerates of lactose and to evaluate their
physicochemical properties, flow properties, particle friability and compaction properties …