Spherical crystallization of drugs
B Kovačič, F Vrečer, O Planinšek - Acta pharmaceutica, 2012 - sciendo.com
Spherical crystallization of drugs is the process of obtaining larger particles by
agglomeration during crystallization. The most common techniques used to obtain such …
agglomeration during crystallization. The most common techniques used to obtain such …
Curcumin nanoparticles improve the physicochemical properties of curcumin and effectively enhance its antioxidant and antihepatoma activities
FL Yen, TH Wu, CW Tzeng, LT Lin… - Journal of agricultural …, 2010 - ACS Publications
Curcumin (CUR), a natural polyphenol isolated from tumeric (Curcuma longa), has been
documented to possess antioxidant and anticancer activities. Unfortunately, the compound …
documented to possess antioxidant and anticancer activities. Unfortunately, the compound …
Crystal engineering for enhanced solubility and bioavailability of poorly soluble drugs
J Varshosaz, E Ghassami… - Current pharmaceutical …, 2018 - ingentaconnect.com
Background: Crystal engineering is dealing with the creation of new structures and new
properties in drug molecules through inter-molecular interactions. Researchers of …
properties in drug molecules through inter-molecular interactions. Researchers of …
[PDF][PDF] Mechanism of dissolution enhancement and bioavailability of poorly water soluble celecoxib by preparing stable amorphous nanoparticles
Y Liu, C Sun, Y Hao, T Jiang… - Journal of pharmacy …, 2010 - frontierspartnerships.org
Purpose: Nanoparticle engineering offers promising methods for the formulation of poorly
water soluble drug compounds. The aim of the present work was to enhance dissolution and …
water soluble drug compounds. The aim of the present work was to enhance dissolution and …
Silica-lipid hybrid (SLH) microcapsules: a novel oral delivery system for poorly soluble drugs
A silica-lipid hybrid (SLH) microcapsule system for oral delivery of poorly water-soluble
drugs is reported for the first time. For the model drug celecoxib (CEL), SLH microcapsules …
drugs is reported for the first time. For the model drug celecoxib (CEL), SLH microcapsules …
Solubility enhancement of BCS Class II drug by solid phospholipid dispersions: Spray drying versus freeze-drying
SYK Fong, A Ibisogly, A Bauer-Brandl - International journal of …, 2015 - Elsevier
The poor aqueous solubility of BCS Class II drugs represents a major challenge for oral
dosage form development. Using celecoxib (CXB) as model drug, the current study adopted …
dosage form development. Using celecoxib (CXB) as model drug, the current study adopted …
[PDF][PDF] Formulation and evaluation of etoricoxib niosomes by thin film hydration technique and ether injection method
V Ravalika, AK Sailaja - Nano Biomed Eng, 2017 - researchgate.net
The main objective of this study is to formulate etoricoxib niosomes as vesicular carriers for
site specific drug delivery. Niosomes are novel vesicular carriers, in which the drug is …
site specific drug delivery. Niosomes are novel vesicular carriers, in which the drug is …
Enabling the drug combination of celecoxib through a spherical co-agglomeration strategy with controllable and stable drug content and good powder properties
S Guo, C Yu, S Feng, J Wei, L Tong, K Li, Y Gao… - International Journal of …, 2022 - Elsevier
Combining celecoxib with other chemopreventive drugs is a promising method of
chemoprevention for cancer, especially for colorectal cancer. However, the traditional drug …
chemoprevention for cancer, especially for colorectal cancer. However, the traditional drug …
In Vitro and In Vivo Evaluation of Proniosomes Containing Celecoxib for Oral Administration
M Nasr - Aaps Pharmscitech, 2010 - Springer
The objectives of this research were to prepare celecoxib proniosomes and evaluate the
influence of proniosomal formulation on the oral bioavailability of the drug in human …
influence of proniosomal formulation on the oral bioavailability of the drug in human …
Spherical agglomerates of lactose with enhanced mechanical properties
D Lamešić, O Planinšek, Z Lavrič, I Ilić - International journal of …, 2017 - Elsevier
The aim of this study was to prepare spherical agglomerates of lactose and to evaluate their
physicochemical properties, flow properties, particle friability and compaction properties …
physicochemical properties, flow properties, particle friability and compaction properties …