The formation of adipocytes during embryogenesis has been largely understudied.
However, preadipocytes appear to originate from multipotent mesenchymal stromal/stem …

Angiogenesis plays an important role in the development of cancer since it allows for the
delivery of oxygen, nutrients, and growth factors as well as tumor dissemination to distant …

Adipocytes arising from mesenchymal stem cells (MSCs) requires MSC adipocyte
commitment and differentiation of preadipocytes to mature adipocytes. Several signaling …

Inflammation is activated by diverse triggers that induce the expression of cytokines and
adhesion molecules, which permit a succession of molecules and cells to deliver stimuli and …

Objective GDF11 is a member of the TGF‐β superfamily that was recently implicated as
potential “rejuvenating” factor, which can ameliorate metabolic disorders. The main objective …

Introduction Mesenchymal stem cells (MSCs) are considered to be the most promising stem
cell type for cell-based therapies in regenerative medicine. Based on their potential to home …

Cancer is a complex disease, with various pre-existing health ailments enhancing its
pathology. In cancer, the extracellular environment contains various intrinsic physiological …

Mesenchymal stem cells (MSCs) are proliferative and multipotent cells that play a key role in
the bone regeneration process. Empirical data have repeatedly shown the bioregulatory …

Growing evidence proves that amino acid restriction can reverse obesity by reducing
adipose tissue mass. Amino acids are not only the building blocks of proteins but also serve …

Background WNT signaling is implicated in embryonic development, and in adult tissue
homeostasis, while its deregulation is evident in disease. This study investigates the unique …