Summary The interleukin (IL)‐36 cytokines include 3 agonists, IL‐36α, IL‐36β, and IL‐36γ
that bind to a common receptor composed of IL‐36R and IL‐1 RA cP to stimulate …

The recently discovered interleukin (IL)‐36 family of cytokines form part of the broader IL‐1
family and are emerging as important mediators of inflammatory disease. The IL‐36 …

Atopic dermatitis (AD) is a chronic Th2 type inflammatory skin disorder. Here we report that
MyD88 signaling is crucial in the pathogenesis of experimental AD induced by vitamin D3 …

Environmental air pollutants including ozone cause severe lung injury and aggravate
respiratory diseases such as asthma and COPD. Here we compared the effect of ozone on …

Allergic diseases, such as asthma, rhinitis, dermatitis, conjunctivitis, and anaphylaxis, have
recently become a global public health concern. According to previous studies, the NLRP 3 …

Abstract Interleukin-33 (IL-33) is a crucial nuclear cytokine that induces the type 2 immune
response and maintains immune homeostasis. The fine-tuned regulation of IL-33 in tissue …

Myeloid differentiation primary response protein 88 (MyD88) is crucial to immune cascades
mediated by Toll-like receptors (TLRs) and interleukin-1 receptors (IL-1Rs). MyD88 …

Introduction The pathogenesis of chronic lung diseases is multifaceted with a major role of
recurrent micro-injuries of the epithelium. While several reports clearly indicated a prominent …

Myeloid differentiation primary response protein 88 (MyD88), an essential adapter protein
used by toll-like receptors (TLR), is a promising target molecule for the treatment of …

Introduction: Myeloid differentiation primary response protein 88 (MyD88) is a critical
adaptor protein involved in Toll-like and IL-1 receptor family signaling controlling innate …