[HTML][HTML] Ionic liquids as protein stabilizers for biological and biomedical applications: A review

NV Veríssimo, FA Vicente, RC de Oliveira… - Biotechnology …, 2022 - Elsevier
Biotechnology has revolutionized science and health care by providing new biomolecules
with biological and medical applications. However, the low stability of several life-saving …

Do Ionic Liquids Exhibit the Required Characteristics to Dissolve, Extract, Stabilize, and Purify Proteins? Past-Present-Future Assessment

P Bharmoria, AA Tietze, D Mondal, TS Kang… - Chemical …, 2024 - ACS Publications
Proteins are highly labile molecules, thus requiring the presence of appropriate solvents and
excipients in their liquid milieu to keep their stability and biological activity. In this field, ionic …

Ionic liquids as biocompatible stabilizers of proteins

M Reslan, V Kayser - Biophysical reviews, 2018 - Springer
Ionic liquids (ILs) have recently emerged as versatile solvents and additives in the field of
biotechnology, particularly as stabilizers of proteins and enzymes. Of interest to the …

Biocompatibility of ionic liquids towards protein stability: A comprehensive overview on the current understanding and their implications

A Kumar, M Bisht, P Venkatesu - International journal of biological …, 2017 - Elsevier
Over the past years since the discovery of ionic liquids (ILs), there is an increased demand
to consider ILs as novel biocompatible co-solvents for proteins. Due to their tunable physical …

Does the stability of proteins in ionic liquids obey the Hofmeister series?

A Kumar, P Venkatesu - International journal of biological macromolecules, 2014 - Elsevier
Understanding the behavior of Hofmeister anions of ionic liquids (ILs) on protein stability
helps to shed light on how the anions interact with proteins in aqueous solution and is a long …

Endeavour to simplify the frustrated concept of protein-ammonium family ionic liquid interactions

I Jha, P Venkatesu - Physical Chemistry Chemical Physics, 2015 - pubs.rsc.org
The large amount of attention earned by ionic liquids (ILs) in the various physical and
chemical sciences has been attributed to their unique, designer nature. In the past few …

Effects of ionic liquids on metalloproteins

AY Patel, KS Jonnalagadda, N Paradis, TD Vaden… - Molecules, 2021 - mdpi.com
In the past decade, innovative protein therapies and bio-similar industries have grown
rapidly. Additionally, ionic liquids (ILs) have been an area of great interest and rapid …

Choline-based amino acid ILs–collagen interaction: enunciating its role in stabilization/destabilization phenomena

A Tarannum, JR Rao, NN Fathima - The Journal of Physical …, 2018 - ACS Publications
Given the potential of productive interaction between choline-based amino acid ionic liquids
(CAAILs) and collagen, we investigated the role of four CAAILs, viz., choline serinate …

Ionic liquids in protein amyloidogenesis: a brief screenshot of the state-of-the-art

VVS Pillai, A Benedetto - Biophysical Reviews, 2018 - Springer
Ionic liquids (ILs) are a vast class of organic non-aqueous electrolytes whose interaction
with biomolecules is receiving great attention for potential applications in bio-nano …

Thermodynamic studies of ionic hydration and interactions for amino acid ionic liquids in aqueous solutions at 298.15 K

DH Dagade, KR Madkar, SP Shinde… - The Journal of Physical …, 2013 - ACS Publications
Amino acid ionic liquids are a special class of ionic liquids due to their unique acid–base
behavior, biological significance, and applications in different fields such as templates in …