Inspired by the biological processes of molecular recognition and transportation across
membranes, nanopore techniques have evolved in recent decades as ultrasensitive …

Proteins are responsible for the occurrence and treatment of many diseases, and therefore
protein sequencing will revolutionize proteomics and clinical diagnostics. Biological …

Natural proteins are composed of 20 proteinogenic amino acids and their post-translational
modifications (PTMs). However, due to the lack of a suitable nanopore sensor that can …

Efforts to sequence single protein molecules in nanopores,,,–have been hampered by the
lack of techniques with sufficient sensitivity to discern the subtle molecular differences …

The implementation of a reliable, rapid, inexpensive, and simple method for whole-proteome
identification would greatly benefit cell biology research and clinical medicine. Proteins are …

Precise identification and quantification of amino acids is crucial for many biological
applications. Here we report a copper (II)-functionalized Mycobacterium smegmatis porin A …

A high throughput single-molecule method for identifying peptides and sequencing proteins
based on nanopores could reduce costs and increase speeds of sequencing, allow the …

Mimicking cellular transport mechanisms to make solid-state smart nanochannels has long
been of great interest for their diverse applications, but it poses a critical synthetic challenge …

DNA sequencing and hence genomics have been transformed over the last decade by the
commercialization of inexpensive, massively parallel, short-read sequencing technology …

Alditols, which have a sweet taste but produce much lower calories than natural sugars, are
widely used as artificial sweeteners. Alditols are the reduced forms of monosaccharide …