The RAGE axis: a relevant inflammatory hub in human diseases

A Rojas, C Lindner, I Schneider, I Gonzalez, J Uribarri - Biomolecules, 2024 - mdpi.com
In 1992, a transcendental report suggested that the receptor of advanced glycation end-
products (RAGE) functions as a cell surface receptor for a wide and diverse group of …

Methylglyoxal and Advanced Glycation End Products (AGEs): Targets for the Prevention and Treatment of Diabetes-Associated Bladder Dysfunction?

AL Oliveira, MG de Oliveira, FZ Mónica, E Antunes - Biomedicines, 2024 - mdpi.com
Methylglyoxal (MGO) is a highly reactive α-dicarbonyl compound formed endogenously from
3-carbon glycolytic intermediates. Methylglyoxal accumulated in plasma and urine of …

Chitosan-Derived Nanocarrier Polymers for Drug Delivery and pH-Controlled Release in Type 2 Diabetes Treatment

S Guo, H Li - Journal of Fluorescence, 2024 - Springer
Abstract Diabetes, particularly Type 2 Diabetes Mellitus (T2DM), is a chronic metabolic
disorder with high and increasing global prevalence, characterized by insulin resistance and …

The RAGE gene crucial function in the etiology and consequences of Type I diabetes

AA Mohamed, MO Mahmoud… - … of Medicine in …, 2024 - jmisr.researchcommons.org
Type I Diabetes, among the ten greatest causes of mortality worldwide, is estimated to afflict
642 million individuals by 2040. It is an auto-immune illness brought on by an association of …