Circulating tumor cells (CTCs) are tumor cells that have sloughed off the primary tumor and
extravasate into and circulate in the blood. Understanding of the metastatic cascade of CTCs …

Abstract Background Cancer stem cells (CSCs) are subpopulations of cancer cells sharing
similar characteristics as normal stem or progenitor cells such as self-renewal ability and …

Abstract CD44/CD24 and ALDH1 are widely used cancer stem cell (CSC) markers in breast
cancer. However, their expression is not always consistent even in the same subtype of …

Tumor relapse and metastasis are the primary causes of poor survival rates in patients with
advanced cancer despite successful resection or chemotherapeutic treatment. A primary …

Presence and frequency of rare circulating tumor cells (CTCs) in bloodstreams of cancer
patients are pivotal to early cancer detection and treatment monitoring. Here, we use a spiral …

Background The identification of circulating tumour cells correlate with poor prognosis in
metastatic breast cancer, but there are few data describing the importance of circulating …

Cancer stem cells (CSCs), the subpopulation of cancer cells, have the capability of
proliferation, self-renewal, and differentiation. The presence of CSCs is a key factor leading …

Metastatic growth in breast cancer (BC) has been proposed as an exclusive property of
cancer stem cells (CSCs). However, formal proof of their identity as cells of origin of …

The cancer stem cell (CSC) concept, which arose more than a decade ago, proposed that
tumor growth is sustained by a subpopulation of highly malignant cancerous cells. These …

Solid tumors derived from epithelial tissues (carcinomas) are responsible for 90% of all new
cancers in Europe, and the main four tumor entities are breast, prostate, lung, and colon …