Melittin (MEL), a major peptide component of bee venom, is an attractive candidate for
cancer therapy. This agent has shown a variety of anti-cancer effects in preclinical cell …

Antimicrobial peptides (AMPs) are part of the innate immune defense mechanism of many
organisms. Although AMPs have been essentially studied and developed as potential …

In spite of great advances in cancer therapy, there is considerable current interest in
developing anticancer agents with a new mode of action because of the development of …

As the key components of innate immunity, human host defense antimicrobial peptides and
proteins (AMPs) play a critical role in warding off invading microbial pathogens. In addition …

Abstract Bee venom (BV)(api-toxin) has been widely used in the treatment of some immune-
related diseases, as well as in recent times in treatment of tumors. Several cancer cells …

Although much progress has been achieved in the development of cancer therapies in
recent decades, problems continue to arise particularly with respect to chemotherapy due to …

During the last two decades cationic amphiphilic peptides and peptide sequences (CAPs)
with cancer-selective toxicity have appeared. Based on their spectrum of anticancer activity …

Bee venom (BV) therapy (BVT), the therapeutic application of BV, has been used in
traditional medicine to treat diseases, such as arthritis, rheumatism, pain, cancerous tumors …

Antibiotic resistance is increasing at a rate that far exceeds the pace of new development of
drugs. Antimicrobial peptides, both synthetic and from natural sources, have raised interest …

Melittin is the principal toxic component in the venom of the European honey bee Apis
mellifera and is a cationic, hemolytic peptide. It is a small linear peptide composed of 26 …