The glycosylation in SARS-CoV-2 and its receptor ACE2

Y Gong, S Qin, L Dai, Z Tian - Signal Transduction and Targeted …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), a highly infectious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected more than …

Okra (Abelmoschus Esculentus) as a Potential Dietary Medicine with Nutraceutical Importance for Sustainable Health Applications

AEO Elkhalifa, E Alshammari, M Adnan, JC Alcantara… - Molecules, 2021 - mdpi.com
Recently, there has been a paradigm shift from conventional therapies to relatively safer
phytotherapies. This divergence is crucial for the management of various chronic diseases …

Developments in carbohydrate-based cancer therapeutics

F Hossain, PR Andreana - Pharmaceuticals, 2019 - mdpi.com
Cancer cells of diverse origins express extracellular tumor-specific carbohydrate antigens
(TACAs) because of aberrant glycosylation. Overexpressed TACAs on the surface of tumor …

Targeted delivery to tumors: multidirectional strategies to improve treatment efficiency

OM Kutova, EL Guryev, EA Sokolova, R Alzeibak… - Cancers, 2019 - mdpi.com
Malignant tumors are characterized by structural and molecular peculiarities providing a
possibility to directionally deliver antitumor drugs with minimal impact on healthy tissues and …

Exploring lectin–glycan interactions to combat COVID-19: Lessons acquired from other enveloped viruses

LC Nascimento da Silva, JSP Mendonça… - …, 2021 - academic.oup.com
The emergence of a new human coronavirus severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has imposed great pressure on the health system worldwide …

Antitumor potential of marine and freshwater lectins

E Catanzaro, C Calcabrini, A Bishayee, C Fimognari - Marine drugs, 2019 - mdpi.com
Often, even the most effective antineoplastic drugs currently used in clinic do not efficiently
allow complete healing due to the related toxicity. The reason for the toxicity lies in the lack …

Computational prediction method to decipher receptor–glycoligand interactions in plant immunity

I Del Hierro, H Melida, C Broyart, J Santiago… - The Plant …, 2021 - Wiley Online Library
Microbial and plant cell walls have been selected by the plant immune system as a source of
microbe‐and plant damage‐associated molecular patterns (MAMPs/DAMPs) that are …

Utilization of novel lectin-conjugated Au nanoparticles as Thomsen-Friedenreich onco-antigen target for in vitro cytotoxicity and apoptosis induction in leukemic cell …

SM Akram, AZ Al-Saffar, NA Hadi, SM Akram - Life Sciences, 2022 - Elsevier
Leukemia is a tumor of blood-forming tissues including bone marrow and lymphatic nodes,
which comprise biologically distinct subgroups. In the present study, Au NPs-PEG-Lectin …

A novel mannose-binding lectin from Liparis nervosa with anti-fungal and anti-tumor activities

N Jiang, Y Wang, J Zhou, R Zheng… - Acta biochimica et …, 2020 - academic.oup.com
Plant lectins are carbohydrate-binding proteins with nonimmune origin, which can reversibly
bind with carbohydrates, agglutinate cells, and precipitate polysaccharides and …

Therapeutic properties of lectins in herbal supplements

KM Mbae, S Umesha, HM Manukumar - Phytochemistry Reviews, 2018 - Springer
Medicinal plants host numerous therapeutic low molecular weight phytochemicals and
macromolecules such as polysaccharides and proteins. Lectins are glycan binding proteins …