Computational network biology: data, models, and applications

C Liu, Y Ma, J Zhao, R Nussinov, YC Zhang, F Cheng… - Physics Reports, 2020 - Elsevier
Biological entities are involved in intricate and complex interactions, in which uncovering the
biological information from the network concepts are of great significance. Benefiting from …

Network motifs: theory and experimental approaches

U Alon - Nature Reviews Genetics, 2007 - nature.com
Transcription regulation networks control the expression of genes. The transcription
networks of well-studied microorganisms appear to be made up of a small set of recurring …

Modularity and stability in ecological communities

J Grilli, T Rogers, S Allesina - Nature communications, 2016 - nature.com
Networks composed of distinct, densely connected subsystems are called modular. In
ecology, it has been posited that a modular organization of species interactions would …

[图书][B] An introduction to systems biology: design principles of biological circuits

U Alon - 2019 - api.taylorfrancis.com
Praise for the first edition:… superb, beautifully written and organized work that takes an
engineering approach to systems biology. Alon provides nicely written appendices to …

Network 'small-world-ness': a quantitative method for determining canonical network equivalence

MD Humphries, K Gurney - PloS one, 2008 - journals.plos.org
Background Many technological, biological, social, and information networks fall into the
broad class of 'small-world'networks: they have tightly interconnected clusters of nodes, and …

Molecular representation learning via heterogeneous motif graph neural networks

Z Yu, H Gao - International Conference on Machine Learning, 2022 - proceedings.mlr.press
We consider feature representation learning problem of molecular graphs. Graph Neural
Networks have been widely used in feature representation learning of molecular graphs …

Pervasive robustness in biological systems

MA Félix, M Barkoulas - Nature Reviews Genetics, 2015 - nature.com
Robustness is characterized by the invariant expression of a phenotype in the face of a
genetic and/or environmental perturbation. Although phenotypic variance is a central …

HiSCF: leveraging higher-order structures for clustering analysis in biological networks

L Hu, J Zhang, X Pan, H Yan, ZH You - Bioinformatics, 2021 - academic.oup.com
Motivation Clustering analysis in a biological network is to group biological entities into
functional modules, thus providing valuable insight into the understanding of complex …

Controlling edge dynamics in complex networks

T Nepusz, T Vicsek - Nature Physics, 2012 - nature.com
The interaction of distinct units in physical, social, biological and technological systems
naturally gives rise to complex network structures. Networks have constantly been in the …

Computational methods for trajectory inference from single‐cell transcriptomics

R Cannoodt, W Saelens, Y Saeys - European journal of …, 2016 - Wiley Online Library
Recent developments in single‐cell transcriptomics have opened new opportunities for
studying dynamic processes in immunology in a high throughput and unbiased manner …