Background: Developmental periods in early life may be particularly vulnerable to impacts of
environmental exposures. Human research on this topic has generally focused on single …

From the use of personal products to our consumption of food, water, and air, people are
exposed to a wide array of agents each day-many with the potential to affect health …

The collection of chemical structure information and associated experimental data for
quantitative structure–activity/property relationship (QSAR/QSPR) modeling is facilitated by …

Abstract The US Environmental Protection Agency (EPA) is faced with the challenge of
efficiently and credibly evaluating chemical safety often with limited or no available toxicity …

Background: Humans are exposed to thousands of man-made chemicals in the
environment. Some chemicals mimic natural endocrine hormones and, thus, have the …

High-throughput in vitro toxicity screening can provide an efficient way to identify potential
biological targets for chemicals. However, relying on nominal assay concentrations may …

Consumer, industrial and commercial product use is a source of exposure to potentially
hazardous chemicals. In addition, cleaning agents, personal care products, coatings and …

The risk posed to human health by any of the thousands of untested anthropogenic
chemicals in our environment is a function of both the hazard presented by the chemical and …

The United States Environmental Protection Agency (US EPA) must characterize potential
risks to human health and the environment associated with manufacture and use of …

Many chemicals in commerce today have undergone limited or no safety testing. To reduce
the number of untested chemicals and prioritize limited testing resources, several …