Spatially well-organized electron-transfer reactions in a series of membrane-bound redox
proteins form the basis for energy conservation in both photosynthesis and respiration. The …

The majority of modern organisms, including many prokaryotes, are aerobes; 1 that is, they
use molecular oxygen as the terminal electron acceptor for energy generation. Although …

The crystal structure at 2.8 Å resolution of the four protein subunits containing cytochrome c
oxidase from the soil bacterium Paracoccus denitrificans, complexed with an antibody Fv …

The high resolution three-dimensional x-ray structure of the metal sites of bovine heart
cytochrome c oxidase is reported. Cytochrome c oxidase is the largest membrane protein yet …

Nitrogen is present in the environment in a number of oxidation states (Fig. 1).
Interconversion between these oxidation states is predominantly biological (Fig. 1). In this …

It has been estimated that about 90% of the reduction of molecular oxygen in the biosphere
is catalyzed by respiratory oxidases (95). Much of this is accomplished by a wide variety of …

▪ Abstract Cytochrome c oxidase, the terminal enzyme of the respiratory chains of
mitochondria and aerobic bacteria, catalyzes electron transfer from cytochrome c to …

Abstract A water-soluble, 62-residue, di-α-helical peptide has been synthesized which
accommodates two bis-histidyl haem groups. The peptide assembles into a four-helix dimer …

▪ Abstract Enzymes of the mitochondrial respiratory chain serve as proton pumps, using the
energy made available from electron transfer reactions to transport protons across the inner …

Biogenesis of respiratory cytochromes is defined as consisting of the posttranslational
processes that are necessary to assemble apoprotein, heme, and sometimes additional …