Glycosylated porphyrins, phthalocyanines, and other porphyrinoids for diagnostics and therapeutics

S Singh, A Aggarwal, NVSDK Bhupathiraju… - Chemical …, 2015 - ACS Publications
As deaths from preventable diseases abate, cancer is becoming one of the leading causes
of death in the world. Photodynamic therapy (PDT) is a noninvasive treatment for cancer …

Photodynamic therapy (PDT) of cancer: from local to systemic treatment

JM Dąbrowski, LG Arnaut - Photochemical & Photobiological Sciences, 2015 - pubs.rsc.org
Photodynamic therapy (PDT) requires a medical device, a photosensitizing drug and
adequate use of both to trigger biological mechanisms that can rapidly destroy the primary …

Porphyrin and phthalocyanine photosensitizers designed for targeted photodynamic therapy of colorectal cancer

K Janas, E Boniewska-Bernacka, G Dyrda… - Bioorganic & medicinal …, 2021 - Elsevier
Colorectal cancer is of particular concern due to its high mortality rate count. Recent
investigations on targeted phototherapy involving novel photosensitizers and drug-delivery …

Carbohydrate–macrocycle conjugates for biomedical applications

F Yin, JJ Li, B Shi, K Zhang, XL Li, KR Wang… - Materials Chemistry …, 2023 - pubs.rsc.org
Carbohydrates are of great importance in a variety of biological processes, including but not
limited to, energy production, energy storage, protein recognition, immune response, and …

Modulation of the electronic and spectroscopic properties of Zn (II) phthalocyanines by their substitution pattern

SZ Topal, Ü İşci, U Kumru, D Atilla, AG Gürek… - Dalton …, 2014 - pubs.rsc.org
Four isomerically pure octasubstituted zinc phthalocyanines with variations in the
attachment atom and positions of the substituents were selected for a systematic …

Fluorination of phthalocyanine substituents: Improved photoproperties and enhanced photodynamic efficacy after optimal micellar formulations

B Pucelik, I Gürol, V Ahsen, F Dumoulin… - European journal of …, 2016 - Elsevier
A fluorinated phthalocyanine and its non-fluorinated analogue were selected to evaluate the
potential enhancement of fluorination on photophysical, photochemical and redox properties …

Folic acid conjugates with photosensitizers for cancer targeting in photodynamic therapy: Synthesis and photophysical properties

A Stallivieri, L Colombeau, G Jetpisbayeva… - Bioorganic & Medicinal …, 2017 - Elsevier
Recent researches in photodynamic therapy have focused on novel techniques to enhance
tumour targeting of anticancer drugs and photosensitizers. Coupling a photosensitizer with …

Synthetic approaches to asymmetric phthalocyanines and their analogues

V Nemykin, S Dudkin, F Dumoulin, C Hirel… - Arkivoc, 2014 - avesis.acibadem.edu.tr
This review summarizes synthetic strategies for the preparation of asymmetric
phthalocyanines and their analogues. Cross-condensation between two phthalonitrile …

Potential of photodynamic therapy based on sugar-conjugated photosensitizers

H Kataoka, H Nishie, M Tanaka, M Sasaki… - Journal of Clinical …, 2021 - mdpi.com
In 2015, the Japanese health insurance approved the use of a second-generation
photodynamic therapy (PDT) using talaporfin sodium (TS); however, its cancer cell …

Porphyrins and related macrocycles: Combining photosensitization with radio-or optical-imaging for next generation theranostic agents

J Sandland, N Malatesti, R Boyle - Photodiagnosis and photodynamic …, 2018 - Elsevier
This review summarises recent research into combining the photosensitizing properties of
porphyrins with imaging techniques such as PET and NIR fluorescence for so called …