Mitochondrial structures were probably observed microscopically in the 1840s, but the idea
of oxidative phosphorylation (OXPHOS) within mitochondria did not appear until the 1930s …

The neuromuscular junction (NMJ) is a specialized synapse that bridges the motor neuron
and the skeletal muscle fiber and is crucial for conversion of electrical impulses originating …

Patients with primary mitochondrial oxidative phosphorylation (OxPhos) defects present with
fatigue and multi-system disorders, are often lean, and die prematurely, but the mechanistic …

Following acute coronavirus disease 2019 (COVID-19), a substantial proportion of patients
showed symptoms and sequelae for several months, namely the postacute sequelae of …

Primary mitochondrial disease (PMD) is a group of complex genetic disorders that arise due
to pathogenic variants in nuclear or mitochondrial genomes. Although PMD is one of the …

In order to identify peripheral biomarkers of impaired oxidative metabolism during exercise
following a 10‐day bed rest, 10 males performed an incremental exercise (to determine …

Simple Summary In recent years, physical exercise has been used as a therapeutic strategy
in various clinical conditions, with pleiotropic benefits. Near-infrared spectroscopy (NIRS) …

During exhaustive ramp-incremental cycling tests, the incidence of O2 uptake (V̇o2)
plateaus is low. To verify the attainment of maximum V̇o2 (V̇o2max), it is recommended …

Carbohydrate availability affects fat metabolism during exercise; however, the effects of
complete muscle glycogen unavailability on maximal fat oxidation (MFO) rate remain …

The integrative response to exercise differs between sexes, with oxidative energy
contribution purported as a potential mechanism. The present study investigated whether …