CD40 is a cell surface receptor that belongs to the tumor necrosis factor‐R (TNF‐R) family,
and that was first identified and functionally characterized on B lymphocytes. Its critical role …

B cell chronic lymphocytic leukemia (B-CLL) is an accumulative disease of slowly
proliferating CD5+ B lymphocytes that develops in the aging population. Whereas some …

Bruton´ s tyrosine kinase (BTK) inhibitor (BTKi) s block the B-cell receptor (BCR) signaling
cascade by binding to the BTK enzyme preventing the proliferation and survival of malignant …

B-cell chronic lymphocytic leukemia (B-CLL) is considered an accumulative disease of
antigen-naive CD5+ B lymphocytes that circulate in the resting state. However, to evaluate …

PURPOSE: To review the recent major advances in the molecular and cell biology of B-cell
chronic lymphocytic leukemia (B-CLL). METHODS: We analyzed the nature of malignant B …

Chronic lymphocytic leukemia (CLL) is an indolent malignancy of CD5+ B lymphocytes. CLL
cells express CD40, a key regulator of B cell proliferation, differentiation, and survival. In …

Scope In vitro and in vivo studies suggest that dietary anthocyanins modulate cardiovascular
disease risk; however, given anthocyanins extensive metabolism, it is likely that their …

Chronic lymphocytic leukemia (CLL) cells cycle between lymphoid tissue sites where they
actively proliferate, and the peripheral blood (PB) where they become quiescent. Strong …

Chronic lymphocytic leukemia (CLL) is an incurable leukemia characterized by the slow but
progressive accumulation of cells in a CD5+ B-cell clone. Like the nonmalignant …

In this review, we summarize the morphological features and immunophenotypic profile of
chronic lymphocytic leukemia (CLL) cells, discuss the value of these investigations as front …