[HTML][HTML] Respiratory allergy caused by house dust mites: what do we really know?

MA Calderón, A Linneberg, J Kleine-Tebbe… - Journal of Allergy and …, 2015 - Elsevier
The house dust mite (HDM) is a major perennial allergen source and a significant cause of
allergic rhinitis and allergic asthma. However, awareness of the condition remains generally …

Danger-associated molecular patterns (DAMPs): the derivatives and triggers of inflammation

S Patel - Current allergy and asthma reports, 2018 - Springer
Abstract Purpose of Review Allergen is an umbrella term for irritants of diverse origin. Along
with other offenders such as pathogens, mutagens, xenobiotics, and pollutants, allergens …

Evolution and predictive value of IgE responses toward a comprehensive panel of house dust mite allergens during the first 2 decades of life

D Posa, S Perna, Y Resch, C Lupinek, V Panetta… - Journal of Allergy and …, 2017 - Elsevier
Background The evolution of the IgE response to the numerous allergen molecules of
Dermatophagoides pteronyssinus is still unknown. Objectives We sought to characterize the …

Lung health in era of climate change and dust storms

MD Schweitzer, AS Calzadilla, O Salamo, A Sharifi… - Environmental …, 2018 - Elsevier
Dust storms are strong winds which lead to particle exposure over extensive areas. These
storms influence air quality on both a local and global scale which lead to both short and …

Single-cell transcriptomic analysis reveals the immune landscape of lung in steroid-resistant asthma exacerbation

L Wang, KG Netto, L Zhou, X Liu… - Proceedings of the …, 2021 - National Acad Sciences
Exaggerated airway hyperresponsiveness and inflammation are hallmarks of asthma, and
lipopolysaccharide (LPS) exposure is linked to the severity of the disease and steroid …

Allergens with protease activity from house dust mites

M Reithofer, B Jahn-Schmid - International journal of molecular sciences, 2017 - mdpi.com
Globally, house dust mites (HDM) are one of the main sources of allergens causing Type I
allergy, which has a high risk of progressing into a severe disabling disease manifestation …

[HTML][HTML] The role of environmental allergen control in the management of asthma

O Kalayci, M Miligkos, CFP Beltrán, ZA El-Sayed… - World Allergy …, 2022 - Elsevier
Allergen exposure may exacerbate asthma symptoms in sensitized patients. Allergen
reduction or avoidance measures have been widely utilized; however, there is ongoing …

Oxidative stress promotes corticosteroid insensitivity in asthma and COPD

BW Lewis, ML Ford, LK Rogers, RD Britt Jr - Antioxidants, 2021 - mdpi.com
Corticosteroid insensitivity is a key characteristic of patients with severe asthma and COPD.
These individuals experience greater pulmonary oxidative stress and inflammation, which …

[HTML][HTML] Mode of dendritic cell activation: the decisive hand in Th2/Th17 cell differentiation. Implications in asthma severity?

H Vroman, B van den Blink, M Kool - Immunobiology, 2015 - Elsevier
Asthma is a heterogeneous chronic inflammatory disease of the airways, with reversible
airflow limitations and airway remodeling. The classification of asthma phenotypes was …

Der f1 induces pyroptosis in human bronchial epithelia via the NLRP3 inflammasome

YM Tsai, KH Chiang, JY Hung… - International …, 2018 - spandidos-publications.com
Damage to the bronchial epithelium leads to persistent inflammation and airway remodelling
in various respiratory diseases, such as asthma and chronic obstructive pulmonary disease …