Abstract GH and IGF-I are important regulators of bone homeostasis and are central to the
achievement of normal longitudinal bone growth and bone mass. Although GH may act …

Pituitary disease is associated with increased mortality predominantly due to vascular
disease. Control of cortisol secretion and GH hypersecretion (and cardiovascular risk factor …

Animal models are fundamentally important in our quest to understand the genetic,
epigenetic, and environmental factors that contribute to human aging. In comparison to …

Context: GH deficiency (GHD) of the adult is a clinical condition characterized by the
presence of several traditional and emerging cardiovascular risk factors that can significantly …

Objective The aim of the present study was to clarify the relationship between GH deficiency
(GHD) and some cardiovascular risk factors and to analyse the effect of GH replacement …

Objective Few studies have determined the effects of more than 5–10 years of GH
replacement in adults on body composition and cardiovascular risk factors. Design/patients …

Objective: GH deficiency is associated with decreased bone mineral density (BMD) and
increased fracture risk. Because the effects of recombinant human GH (rhGH) therapy on …

Objective: GH deficiency is associated with decreased bone mineral density (BMD) and
increased fracture risk. Because the effects of recombinant human GH (rhGH) therapy on …

GH has a significant impact on body composition due to distinct anabolic and catabolic
effects on lean and fat mass, respectively. Several studies have assessed body composition …

Adult growth hormone deficiency (GHD) is a well defined clinical condition, which is
characterized by abnormal body composition, impaired physical activity and decreased …