In the last two decades, solid-state nuclear magnetic resonance (ssNMR) spectroscopy has
transformed from a spectroscopic technique investigating small molecules and industrial …

Biological membranes and membrane proteins, responsible for numerous exciting
biological processes, present one of the paramount challenges in biophysics today …

► Lipid bicelles have matured to full membership in the club of lipid phases.► Numerous
techniques have elucidated the character traits of bicelles.► Bicelles are exemplary citizens …

In this chapter, we summarize the isotopic labeling strategies used to obtain high-quality
solution and solid-state NMR spectra of biological samples, with emphasis on integral …

Multiplexing NMR experiments by direct detection of multiple free induction decays (FIDs) in
a single experiment offers a dramatic increase in the spectral information content and often …

Unlike water soluble proteins, the structures of helicaltransmembrane proteins depend on a
very complex environment. These proteins sit in the midst of dramatic electrical and …

Solid-state NMR spectroscopy has been used successfully for characterizing the structure
and dynamics of membrane proteins as well as their interactions with other proteins in lipid …

We used oriented solid-state NMR spectroscopy and biochemical cross-linking experiments
to demonstrate that the ligand-free membrane protein transporter EmrE forms anti-parallel …

Phospholamban (PLN) is a mini-membrane protein that directly controls the cardiac Ca2+-
transport response to β-adrenergic stimulation, thus modulating cardiac output during the …

Antimicrobial peptides (AMPs) provide a primordial source of immunity, conferring upon
eukaryotic cells resistance against bacteria, protozoa, and viruses. Despite a few examples …