Nutrients, foods, and colorectal cancer prevention

M Song, WS Garrett, AT Chan - Gastroenterology, 2015 - Elsevier
Diet has an important role in the development of colorectal cancer. In the past few decades,
findings from extensive epidemiologic and experimental investigations have linked …

Selenium in cancer prevention: a review of the evidence and mechanism of action

MP Rayman - Proceedings of the Nutrition Society, 2005 - cambridge.org
Se is an unusual trace element in having its own codon in mRNA that specifies its insertion
into selenoproteins as selenocysteine (SeCys), by means of a mechanism requiring a large …

[HTML][HTML] International natural product sciences taskforce

AG Atanasov, SB Zotchev, VM Dirsch… - Nat. Rev. Drug Discov, 2021 - inpst.net
Background: This# DoesItWorkSummary is based on the findings of a systematic review and
meta-analysis published in The Lancet journal in September 2018 [1]. Alcohol has …

Antioxidant activity of sulfur and selenium: a review of reactive oxygen species scavenging, glutathione peroxidase, and metal-binding antioxidant mechanisms

EE Battin, JL Brumaghim - Cell biochemistry and biophysics, 2009 - Springer
It is well known that oxidation caused by reactive oxygen species (ROS) is a major cause of
cellular damage and death and has been implicated in cancer, neurodegenerative, and …

n‐3 Omega fatty acids: a review of current knowledge

U Gogus, C Smith - International journal of food science & …, 2010 - Wiley Online Library
The very long chain polyunsaturated fatty acids (PUFAs)(C18–C22) and n‐3 Omega PUFAs
are apparently widely accepted as a part of modern nutrition because of their beneficial …

Regulation and function of selenoproteins in human disease

FP Bellinger, AV Raman, MA Reeves… - Biochemical …, 2009 - portlandpress.com
Selenoproteins are proteins containing selenium in the form of the 21st amino acid,
selenocysteine. Members of this protein family have many diverse functions, but their …

Selenium: a double-edged sword for defense and offence in cancer

J Brozmanová, D Mániková, V Vlčková… - Archives of toxicology, 2010 - Springer
Selenium (Se) is an essential dietary component for animals including humans and is
regarded as a protective agent against cancer. Although the mode of anticancer action of Se …

Selenium, oxidative stress, and health aspects

P Brenneisen, H Steinbrenner, H Sies - Molecular aspects of medicine, 2005 - Elsevier
Metabolic processes which generate oxidants and antioxidants are governed by genetic
disposition as well as environmental factors. Changes in lifestyle, including increased …

Human selenoproteins at a glance

S Gromer, JK Eubel, BL Lee, J Jacob - Cellular and Molecular Life …, 2005 - Springer
The public perception of selenium has changed significantly over the last decades.
Originally mainly known for its high toxicity, it was later recognized as an essential trace …

Thioredoxin reductase 1 deficiency reverses tumor phenotype and tumorigenicity of lung carcinoma cells

MH Yoo, XM Xu, BA Carlson, VN Gladyshev… - Journal of Biological …, 2006 - ASBMB
Dietary selenium has potent cancer prevention activity. Both low molecular weight
selenocompounds and selenoproteins are implicated in this effect. Thioredoxin reductase 1 …