Metallo-drugs in cancer therapy: Past, present and future

RL Lucaciu, AC Hangan, B Sevastre, LS Oprean - Molecules, 2022 - mdpi.com
Cancer treatments which include conventional chemotherapy have not proven very
successful in curing human malignancies. The failures of these treatment modalities include …

Integration of cyclodextrins and associated toxicities: A roadmap for high quality biomedical applications

F Trotta, T Loftsson, RS Gaud, R Trivedi… - Carbohydrate Polymers, 2022 - Elsevier
Cyclodextrins are extensively employed in drug delivery systems like inclusion complexes,
metal-organic frameworks, functionalized or PEGylated conjugates, and other nanocarrier …

Anthocyanins and carotenoids characterization in flowers and leaves of cyclamen genotypes linked with bioactivities using multivariate analysis techniques

M Cornea-Cipcigan, A Bunea, CM Bouari, D Pamfil… - Antioxidants, 2022 - mdpi.com
The present study was carried out to evaluate and compare in vitro antioxidant (2, 2-
diphenyl-1-picrylhydrazyl (DPPH), Trolox equivalent antioxidant capacity (TEAC), and ferric …

Chemical Profile, Cytotoxic Activity and Oxidative Stress Reduction of Different Syringa vulgaris L. Extracts

D Hanganu, M Niculae, I Ielciu, NK Olah, M Munteanu… - Molecules, 2021 - mdpi.com
Syringa vulgaris L.(common lilac) is one of the most popular ornamental species, but also a
promising not comprehensively studied source of bioactive compounds with important …

Antiproliferative and Antimicrobial Effects of Rosmarinus officinalis L. Loaded Liposomes

I Ielciu, M Niculae, E Pall, C Barbălată, I Tomuţă… - Molecules, 2022 - mdpi.com
Rosmarinus officinalis L. is a species that is widely known for its culinary and medicinal
uses. The purpose of the present study consisted of the evaluation of the antiproliferative …

Phytochemical Characterization of Taxus baccata L. Aril with Emphasis on Evaluation of the Antiproliferative and Pro-Apoptotic Activity of Rhodoxanthin

DA Dumitraş, A Bunea, DC Vodnar, D Hanganu, E Pall… - Antioxidants, 2022 - mdpi.com
Taxus baccata L., an evergreen tree, was known until recently due to its high concentration
of toxic compounds. The purpose of the present study was to focus on the only non …

Trans-2-hexenal/β-cyclodextrin effectively reduces green mold in citrus fruit

Y Zhang, Q OuYang, B Duan, OO Reymick… - Postharvest Biology and …, 2022 - Elsevier
Green mold, caused by Penicillium digitatum, is the primary postharvest disease in citrus
fruit. Trans-2-hexenal was found to exert a considerable inhibitory effect on the mycelial …

Amygdalin-folic acid-nanoparticles inhibit the proliferation of breast cancer and enhance the effect of radiotherapy through the modulation of tumor-promoting factors …

MA Askar, GS El-Sayyad, MS Guida, E Khalifa… - … Medicine and Therapies, 2023 - Springer
Introduction Breast cancer (BC) cells often develop multiple mechanisms of chemo-and
radio-resistance during tumor progression, which is the major reason for the failure of breast …

New Cu+2 Complexes with N-Sulfonamide Ligands: Potential Antitumor, Antibacterial, and Antioxidant Agents

AC Hangan, A Turza, RL Lucaciu, B Sevastre, E Páll… - Molecules, 2022 - mdpi.com
Nowadays, the discovery of a new non-toxic metal complex with biological activity
represents a very active area of research. Two Cu+ 2 complexes,[Cu (L1) 2 (H2O) …

Formation of amygdalin/β-cyclodextrin derivatives inclusion complexes for anticancer activity assessment in human cervical carcinoma HeLa cell line

V Meenatchi, KB Narayanan, A Sood… - International Journal of …, 2024 - Elsevier
Nanoencapsulation has gained considerable attention because of its unique features and
advantages in anticancer drug delivery. Amygdalin (AMY) is an anticancer compound …