Cryopreservation: an overview of principles and cell-specific considerations
D Whaley, K Damyar, RP Witek… - Cell …, 2021 - journals.sagepub.com
The origins of low-temperature tissue storage research date back to the late 1800s. Over half
a century later, osmotic stress was revealed to be a main contributor to cell death during …
a century later, osmotic stress was revealed to be a main contributor to cell death during …
Male infertility due to testicular disorders
Context Male infertility is defined as the inability to conceive following 1 year of regular
unprotected intercourse. It is the causative factor in 50% of couples and a leading indication …
unprotected intercourse. It is the causative factor in 50% of couples and a leading indication …
[HTML][HTML] Mitochondrial dysfunction and oxidative stress caused by cryopreservation in reproductive cells
Mitochondria, fundamental organelles in cell metabolism, and ATP synthesis are
responsible for generating reactive oxygen species (ROS), calcium homeostasis, and cell …
responsible for generating reactive oxygen species (ROS), calcium homeostasis, and cell …
Ultrasound of the male genital tract in relation to male reproductive health
BACKGROUND Infertility affects∼ 7% of all men. Despite much progress, mainly in
genetics, its etiology remains obscure in∼ 50% of cases. To fill this gap, imaging of the male …
genetics, its etiology remains obscure in∼ 50% of cases. To fill this gap, imaging of the male …
[HTML][HTML] Sperm oxidative stress during in vitro manipulation and its effects on sperm function and embryo development
R Gualtieri, G Kalthur, V Barbato, S Longobardi… - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) generated at low levels during mitochondrial respiration
have key roles in several signaling pathways. Oxidative stress (OS) arises when the …
have key roles in several signaling pathways. Oxidative stress (OS) arises when the …
[HTML][HTML] Cryopreservation of human spermatozoa: Functional, molecular and clinical aspects
L Tamburrino, G Traini, A Marcellini, L Vignozzi… - International journal of …, 2023 - mdpi.com
Cryopreservation is an expanding strategy to allow not only fertility preservation for
individuals who need such procedures because of gonadotoxic treatments, active duty in …
individuals who need such procedures because of gonadotoxic treatments, active duty in …
[HTML][HTML] Semen quality of 4480 young cancer and systemic disease patients: baseline data and clinical considerations
J Auger, N Sermondade, F Eustache - Basic and clinical andrology, 2016 - Springer
Background Except for testicular cancer and Hodgkin's disease, baseline data on semen
quality in case of cancers as well as systemic pathologies of the young adult are scarce or …
quality in case of cancers as well as systemic pathologies of the young adult are scarce or …
[HTML][HTML] Fertility preservation in pediatric healthcare: a review
L Chen, Z Dong, X Chen - Frontiers in Endocrinology, 2023 - frontiersin.org
Survival rates for children and adolescents diagnosed with malignancy have been steadily
increasing due to advances in oncology treatments. These treatments can have a toxic effect …
increasing due to advances in oncology treatments. These treatments can have a toxic effect …
[HTML][HTML] Process and pitfalls of sperm cryopreservation
H Rozati, T Handley, C Jayasena - Journal of clinical medicine, 2017 - mdpi.com
Sperm cryopreservation has been utilized routinely for over 40 years to preserve fertility in
men undergoing cancer therapy and allow conception for infertile couples. This article …
men undergoing cancer therapy and allow conception for infertile couples. This article …
[HTML][HTML] Testicular and haematological cancer induce very high levels of sperm oxidative stress
C Calamai, O Ammar, V Rosta, G Farnetani, S Zimmitti… - Antioxidants, 2023 - mdpi.com
Cancer impairs spermatogenesis, whereas results on sperm DNA integrity are controversial
and no data are available about sperm oxidative stress. In cancer patients, we detected …
and no data are available about sperm oxidative stress. In cancer patients, we detected …