Background In heart failure with reduced left ventricular ejection fraction (HFrEF) patients the
effects of exercise-based cardiac rehabilitation on top of state-of-the-art pharmacological …

Background: Despite developments in surgical techniques and medical care, people with a
Fontan circulation still experience long-term complications; non-invasive therapies to …

Aims OUTSTEP‐HF compared the effect of sacubitril/valsartan vs. enalapril on 6‐min walk
test (6MWT) distance, non‐sedentary daytime physical activity and heart failure (HF) …

Background Improvement in exercise capacity is a main goal of cardiac rehabilitation but the
effects are often lost at long-term follow-up and thus also the benefits on prognosis. We …

Aims Despite the benefits of exercise training in the secondary prevention of cardiovascular
disease, there are conflicting findings for the impact of exercise-based cardiac rehabilitation …

Background: Scientific guidelines have been developed to update and harmonize exercise
based cardiac rehabilitation (ebCR) in German speaking countries. Key recommendations …

Dilated cardiomyopathy associated with lamin A/C (LMNA) gene variants (LMNA-related
dilated cardiomyopathy [DCM]) is a life-threatening condition with a high unmet need …

Heart transplantation is considered the definitive treatment for patients with end-stage heart
failure in whom conventional medical therapy has failed. Patients awaiting heart …

Background Cardiac rehabilitation (CR) has been successful in improving exercise capacity
(EC) and quality of life (QoL). However, depression and anxiety are highly prevalent among …

Exercise has proven cardiac benefits, but the underlying mechanisms of exercise that
protect the heart from acute sympathetic stress injuries remain unknown. In this study, adult …