Evolving concepts in the pathogenesis of uraemic cardiomyopathy

X Wang, JI Shapiro - Nature Reviews Nephrology, 2019 - nature.com
The term uraemic cardiomyopathy refers to the cardiac abnormalities that are seen in
patients with chronic kidney disease (CKD). Historically, this term was used to describe a …

Insulin resistance in chronic kidney disease: a systematic review

B Spoto, A Pisano, C Zoccali - American Journal of …, 2016 - journals.physiology.org
Insulin resistance (IR) is an early metabolic alteration in chronic kidney disease (CKD)
patients, being apparent when the glomerular filtration rate is still within the normal range …

Glycemic management in ESRD and earlier stages of CKD

ME Williams, R Garg - American journal of kidney diseases, 2014 - Elsevier
The management of hyperglycemia in patients with kidney failure is complex, and the goals
and methods regarding glycemic control in chronic kidney disease (CKD) are not clearly …

Randomized cross-over trial of short-term water-only fasting: metabolic and cardiovascular consequences

BD Horne, JB Muhlestein, DL Lappe, HT May… - Nutrition, Metabolism …, 2013 - Elsevier
Background and aims Routine, periodic fasting is associated with a lower prevalence of
coronary artery disease (CAD). Animal studies show that fasting may increase longevity and …

[HTML][HTML] Flipping the molecular switch for innate protection and repair of tissues: Long-lasting effects of a non-erythropoietic small peptide engineered from …

M Collino, C Thiemermann, A Cerami… - Pharmacology & …, 2015 - Elsevier
Many disease processes activate a cellular stress response that initiates a cascade of
inflammation and damage. However, this process also triggers a tissue protection and repair …

Erythropoietin ameliorates cognitive deficits by improving hippocampal and synaptic damage in streptozotocin-induced diabetic mice

W Yan, T Guo, N Liu, X Cui, X Wei, Y Sun, H Hu… - Cellular …, 2023 - Elsevier
Recent studies have shown that erythropoietin (EPO) is an effective neuroprotective and
neurotrophic agent for neurological disorders, such as traumatic brain injury and Alzheimer's …

Echocardiographic manifestations in end-stage renal disease

T Ito, K Akamatsu - Heart Failure Reviews, 2024 - Springer
End-stage renal disease (ESRD) is a common but profound clinical condition, and it is
associated with extremely increased morbidity and mortality. ESRD can represent four major …

[HTML][HTML] Erythropoietin inhibits gluconeogenesis and inflammation in the liver and improves glucose intolerance in high-fat diet-fed mice

R Meng, D Zhu, Y Bi, D Yang, Y Wang - PloS one, 2013 - journals.plos.org
Erythropoietin (EPO) has multiple biological functions, including the modulation of glucose
metabolism. However, the mechanisms underlying the action of EPO are still obscure. This …

[HTML][HTML] Erythropoietin ameliorates PA-induced insulin resistance through the IRS/AKT/FOXO1 and GSK-3β signaling pathway, and inhibits the inflammatory response …

H Zhang, Z Ge, S Tang, R Meng… - Molecular medicine …, 2017 - spandidos-publications.com
Erythropoietin (EPO) contributes to insulin resistance in fat and muscle. In the present study,
the role and mechanism of EPO in hepatic insulin resistance were investigated in HepG2 …

Diabetes management in the kidney patient

R Garg, ME Williams - Medical Clinics, 2013 - medical.theclinics.com
Contributing factors to the abnormalities in glucose homeostasis in people with kidney
impairment are shown in Fig. 1. Multifactorial alterations in glucose homeostasis occur when …