Chinese prickly ash is known for producing a typical pungent sensation in Sichuan Cuisine.
Accumulating evidence suggest a series of health benefits and pharmacological effects …

Abstract Poly (ADP-ribose) polymerase-1 (PARP-1) is the most extensively studied member
of the PARP superfamily, with its primary function being the facilitation of DNA damage …

Background Local neuroinflammation secondary to spinal nerve compression in lumbar disk
herniation (LDH) is a key driver contributing to neuropathic pain. Manual therapy (MT), a …

The wingless-related integration site (Wnt) signaling pathway plays an essential role in
embryonic development and nervous system regulation. It is critically involved in multiple …

Accumulating evidence suggests the key role of the kynurenine pathway (KP) of the
tryptophan metabolism in the pathogenesis of several diseases. Despite extensive research …

Background Neuropathic pain (NP) is the comorbidity in spinal cord injury (SCI), which is the
hardest to cure. Non-coding RNA dysregulations are related to the development of NP …

Neuropathic pain (NP) is a complex health problem that includes sensorial manifestations
such as evoked and ongoing pain. Cannabidiol (CBD) has shown potential in the treatment …

Emerging evidence has implicated poly-(ADP-ribose) polymerase 1 (PARP-1), a
transcriptional coregulator, in a variety of inflammatory diseases. In the current study, the …

Objective The objective of this systematic review and meta-analysis was to assess the
efficacy of exercise in neuropathic pain following traumatic spinal cord injuries. Methods The …

Neuropathic pain is a chronic disease that severely afflicts the life and emotional status of
patients, but currently available treatments are often ineffective. Novel therapeutic targets for …