Background Noninvasive respiratory support (NIRS) has been diffusely employed outside
the intensive care unit (ICU) to face the high request of ventilatory support due to the …

Non-invasive respiratory support (NIRS) has increasingly been used in the management of
COVID-19-associated acute respiratory failure, but questions remain about the utility, safety …

Background The intensity of inflammation during COVID-19 is related to adverse outcomes.
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is involved in low-density lipoprotein …

Noninvasive respiratory support and awake prone position are tools possibly capable of
averting endotracheal intubation in COVID-19 patients; carefully monitoring during any …

Background Whether prone position (PP) improves clinical outcomes in COVID-19
pneumonia treated with noninvasive ventilation (NIV) is unknown. We evaluated the effect of …

The efficacy of non-invasive ventilation (NIV) in acute respiratory failure secondary to SARS-
CoV-2 infection remains controversial. Current literature mainly examined efficacy, safety …

Background As delayed intubation may worsen the outcome of coronavirus disease 2019
(COVID-19) patients treated with continuous positive airway pressure (CPAP), we sought to …

Introduction Assessment of inpatient mortality risk in COVID-19 patients is important for
guiding clinical decision-making. High sensitivity cardiac troponin T (hs-cTnT) is a biomarker …

COVID-19 spread in two pandemic waves in Italy between 2020 and 2021. The aim of this
study is to compare the first with the second COVID-19 wave, analyzing modifiable and non …

Background Continuous positive airway pressure (CPAP) therapy is commonly used for
respiratory failure due to severe COVID-19 pneumonitis, including in patients deemed not …