Late-stage functionalization (LSF) constitutes a powerful strategy for the assembly or
diversification of novel molecular entities with improved physicochemical or biological …

Although electrochemical strategies for small-molecule synthesis are flourishing, this
technology has yet to be fully exploited for the mild and chemoselective modification of …

As the aromatic tryptophan (Trp) side chain plays a pivotal role in influencing the structure
and function of peptides and proteins, it has become an attractive target for the late‐stage …

Electrochemical transformations provide enticing opportunities for programmable, residue‐
specific peptide modifications. Herein, we harness the potential of amidic side‐chains as …

With the increasing importance of peptides in the treatment of oncological diseases and
biomedical applications, the development and construction of new methods for peptide …

Mild strategies for the selective modification of peptides and proteins are in demand for
applications in therapeutic peptide and protein discovery, and in the study of fundamental …

An electrochemical cross-dehydrogenative coupling of indoles with xanthenes has been
established at room temperature. This coupling reaction could proceed in the absence of …

Here we report a simple electrochemical route towards the synthesis of S‐arylated peptides
by a site selective coupling of peptides with aryl halides under base free conditions. This …

A catalyst-free electrochemical [3+ 2] cycloaddition of azobenzenes with hexahydro-1, 3, 5-
triazines in the absence of any external oxidant is developed for constructing the 1, 2, 4 …

Herein, we report an electrochemically promoted chemoselective hydroxyl group
transformation for accessing tyrosine-containing biomolecules with valuable anthranilic acid …