Brain network communication: concepts, models and applications
Understanding communication and information processing in nervous systems is a central
goal of neuroscience. Over the past two decades, advances in connectomics and network …
goal of neuroscience. Over the past two decades, advances in connectomics and network …
Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?
Alzheimer disease (AD) is the most common form of neurodegenerative disease, estimated
to contribute 60–70% of all cases of dementia worldwide. According to the prevailing …
to contribute 60–70% of all cases of dementia worldwide. According to the prevailing …
Frontotemporal lobar degeneration
Frontotemporal lobar degeneration (FTLD) is one of the most common causes of early-onset
dementia and presents with early social–emotional–behavioural and/or language changes …
dementia and presents with early social–emotional–behavioural and/or language changes …
The human connectome in Alzheimer disease—relationship to biomarkers and genetics
The pathology of Alzheimer disease (AD) damages structural and functional brain networks,
resulting in cognitive impairment. The results of recent connectomics studies have now …
resulting in cognitive impairment. The results of recent connectomics studies have now …
Connectome-based modelling of neurodegenerative diseases: towards precision medicine and mechanistic insight
JW Vogel, N Corriveau-Lecavalier… - Nature Reviews …, 2023 - nature.com
Neurodegenerative diseases are the most common cause of dementia. Although their
underlying molecular pathologies have been identified, there is substantial heterogeneity in …
underlying molecular pathologies have been identified, there is substantial heterogeneity in …
Regional Aβ-tau interactions promote onset and acceleration of Alzheimer's disease tau spreading
Amyloid-beta and tau are key molecules in the pathogenesis of Alzheimer's disease, but it
remains unclear how these proteins interact to promote disease. Here, by combining cross …
remains unclear how these proteins interact to promote disease. Here, by combining cross …
Network neuroscience
DS Bassett, O Sporns - Nature neuroscience, 2017 - nature.com
Despite substantial recent progress, our understanding of the principles and mechanisms
underlying complex brain function and cognition remains incomplete. Network neuroscience …
underlying complex brain function and cognition remains incomplete. Network neuroscience …
Imaging the evolution and pathophysiology of Alzheimer disease
W Jagust - Nature Reviews Neuroscience, 2018 - nature.com
Technologies for imaging the pathophysiology of Alzheimer disease (AD) now permit
studies of the relationships between the two major proteins deposited in this disease …
studies of the relationships between the two major proteins deposited in this disease …
Communication dynamics in complex brain networks
A Avena-Koenigsberger, B Misic… - Nature reviews …, 2018 - nature.com
Neuronal signalling and communication underpin virtually all aspects of brain activity and
function. Network science approaches to modelling and analysing the dynamics of …
function. Network science approaches to modelling and analysing the dynamics of …
Local molecular and global connectomic contributions to cross-disorder cortical abnormalities
Numerous brain disorders demonstrate structural brain abnormalities, which are thought to
arise from molecular perturbations or connectome miswiring. The unique and shared …
arise from molecular perturbations or connectome miswiring. The unique and shared …