Background With the technological advances, microsurgery has evolved to the era of
supermicrosurgery since its inception. With the popularization of these flaps, proficiency in …

Background Despite a plethora of monitoring techniques reported in the literature, only a
small number of studies directly address clinical relevant end points, such as the flap …

Background Veliparib is a potent small molecule inhibitor of PARP-1/2, which is cytotoxic in
tumor cells with deficiencies in BRCA1 or BRCA2. We studied the clinical activity and toxicity …

Free tissue transfer is widely used for the reconstruction of complex tissue defects. The
survival of free flaps depends on the patency and integrity of the microvascular anastomosis …

Free tissue transfer is commonly employed in the reconstruction of large or complicated
defects. Postoperative flap failure from microvascular compromise is an uncommon but …

Fibula free flaps (FFF) represent a working horse for different reconstructive scenarios in
facial surgery. While FFF were initially established for mandible reconstruction …

The use of microvascular anastomoses to allow transfer of viable tissue is a fundamental
technique of reconstructive surgery, and is used to treat a broad spectrum of clinical …

Background Among the many factors involved in reconstructive microsurgery, identifying a
good recipient vessel is one of the key elements leading to a successful result. Methods …

Recent advances in technology have shown promise in improving outcomes in
microsurgery. Although vascular compromise and flap loss represent major complications …

Improvements in technique, technology, and monitoring continue to improve success rates,
reduce operative time and associated morbidity, improve overall functional outcomes, and …